SCHEMBL29376366

SCHEMBL29376366

C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)CN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 4/20 0.46
▸ OPRM1 P35372 4/20 0.46
▸ OPRD1 P41143 4/20 0.46
▸ GRB2 P62993 1/20 0.43
▸ BDKRB2 P30411 6/20 0.41
▸ CTSB P07858 1/20 0.41
▸ APLNR P35414 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30167004 1.00 CAPN1 (0.46) CAPN1OPRM1OPRD1GRB2BDKRB2
SCHEMBL29375301 1.00 CAPN1 (0.46) CAPN1OPRM1OPRD1GRB2BDKRB2
SCHEMBL29373267 0.95 CAPN1 (0.44) CAPN1OPRM1OPRD1GRB2BDKRB2
SCHEMBL29691873 0.95 CAPN1 (0.47) CAPN1OPRM1OPRD1GRB2BDKRB2
SCHEMBL31752319 0.95 CAPN1 (0.46) CAPN1OPRM1OPRD1GRB2BDKRB2
SCHEMBL29397223 0.95 CAPN1 (0.46) CAPN1OPRM1OPRD1GRB2BDKRB2
SCHEMBL30211911 0.95 OPRM1 (0.46) CAPN1OPRM1OPRD1CTSBAPLNR
SCHEMBL30647293 0.93 CAPN1 (0.54) CAPN1OPRM1OPRD1GRB2BDKRB2
SCHEMBL29373242 0.93 OPRM1 (0.46) CAPN1OPRM1OPRD1GRB2BDKRB2
SCHEMBL30211914 0.92 OPRM1 (0.45) CAPN1OPRM1OPRD1GRB2APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745153-A1 GLP-1, GIP AND GCG RECEPTOR TRIAGONIST AND USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-05-20 — — EP claimed
WO-2025016303-A1 GLP-1, GIP AND GCG RECEPTOR TRIAGONIST AND USE THEREOF 北京拓界生物医药科技有限公司 2025-01-23 — — WO claimed
US-20240209054-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2024-06-27 — — US claimed
US-11814417-B2 GIP agonist compounds and methods ZEALAND PHARMA A/S (DK) 2023-11-14 — — US claimed
EP-3985016-A1 GIP AGONIST COMPOUNDS AND METHODS Zealand Pharma A/S (DK) 2022-04-20 — — EP claimed
US-20220041676-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2022-02-10 — — US claimed
EP-4745153-A1 GLP-1, GIP AND GCG RECEPTOR TRIAGONIST AND USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-05-20 — — EP disclosed
WO-2025016303-A1 GLP-1, GIP AND GCG RECEPTOR TRIAGONIST AND USE THEREOF 北京拓界生物医药科技有限公司 2025-01-23 — — WO disclosed
US-20240209054-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2024-06-27 — — US disclosed
US-11814417-B2 GIP agonist compounds and methods ZEALAND PHARMA A/S (DK) 2023-11-14 — — US disclosed
US-20230303640-A1 EXENDIN-4 PEPTIDE ANALOGS TXP PHARMA AG (CH) 2023-09-28 — — US disclosed
EP-4144362-A1 COMPOSITIONS COMPRISING SHORT-ACTING HORMONES FOR TREATING OR PREVENTING OBESITY AND PUMPS COMPRISING SAID COMPOSITION Adocia (FR) 2023-03-08 — — EP disclosed
CN-115572326-A Triplex agonists of GLP-1, GCG and GIP receptors 广东东阳光药业有限公司 2023-01-06 — — CN disclosed
CN-115057910-A Complement activity regulator, preparation method and medical application thereof 上海翰森生物医药科技有限公司 2022-09-16 — — CN disclosed
EP-3985016-A1 GIP AGONIST COMPOUNDS AND METHODS Zealand Pharma A/S (DK) 2022-04-20 — — EP disclosed
US-20220041676-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209054-A1 GIP AGONIST COMPOUNDS AND METHODS GIPR, GLP1R, GPR119 CAPN1 3702/4885OPRM1 1117/4885OPRD1 1008/4885
US-11814417-B2 GIP agonist compounds and methods GIPR, GLP1R, GPR119 CAPN1 3702/4885OPRM1 1117/4885OPRD1 1008/4885
US-20220041676-A1 GIP AGONIST COMPOUNDS AND METHODS GIPR, GLP1R, GPR119 CAPN1 3702/4885OPRM1 1117/4885OPRD1 1008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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