Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.57 |
| ▸ | KDM5A | P29375 | 5/20 | 0.57 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.55 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.55 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18579666 | 0.75 | KDM4C (0.67) | KDM5BKDM4CKDM5APHF8KDM2B | |
| SCHEMBL16034040 | 0.73 | KDM4C (1.00) | KDM5BKDM4CKDM5APHF8KDM2B | |
| SCHEMBL29373849 | 0.72 | PHF8 (0.59) | KDM5BKDM4CKDM5APHF8KDM2B | |
| SCHEMBL17604583 | 0.71 | PHF8 (0.68) | KDM5BKDM4CKDM5APHF8KDM2B | |
| SCHEMBL24244255 | 0.69 | PHF8 (0.66) | KDM5BKDM4CKDM5APHF8KDM2B | |
| SCHEMBL19383509 | 0.69 | PHF8 (0.57) | KDM5BKDM4CKDM5APHF8KDM2B | |
| SCHEMBL29376437 | 0.69 | KDM4C (0.57) | KDM5BKDM4CKDM5APHF8KDM2B | |
| SCHEMBL24804227 | 0.65 | KDM2B (0.47) | KDM5BKDM4CKDM5APHF8KDM2B | |
| SCHEMBL24803256 | 0.63 | KDM5A (0.44) | KDM5BKDM4CKDM5APHF8KDM2B | |
| SCHEMBL30268901 | 0.61 | KDM5A (0.62) | KDM5BKDM4CKDM5APHF8KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |