SCHEMBL29377899

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1469806	1.00	MAPT (0.50)	MAPTLMNAALDH1A1TDP1HTT
	SCHEMBL5584373	0.97	MAPT (0.49)	MAPTLMNAALDH1A1TDP1HTT
	SCHEMBL29378637	0.94	PTPN11 (0.48)	MAPTLMNAALDH1A1TDP1HTT
	SCHEMBL17920219	0.94	PTPN11 (0.48)	MAPTLMNAALDH1A1TDP1HTT
	SCHEMBL1467779	0.94	PTPN11 (0.48)	MAPTLMNAALDH1A1TDP1HTT
	SCHEMBL6057276	0.94	PTPN11 (0.48)	MAPTLMNAALDH1A1TDP1HTT
	SCHEMBL3690940	0.92	PTPN11 (0.52)	MAPTLMNAALDH1A1GAAMAPK10
	SCHEMBL30899200	0.92	PTPN11 (0.52)	MAPTLMNAALDH1A1GAAMAPK10
	SCHEMBL4215764	0.91	PTPN11 (0.54)	LMNAGAAMAPK10CNR1CNR2
	SCHEMBL7125656	0.91	PTPN11 (0.54)	LMNAGAAMAPK10CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.