Zingerone

Zingerone

SCHEMBL29378477

COc1cc(CCC(C)=O)ccc1O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.74
OR51E2 Q9H255 1/20 0.74
TAAR1 Q96RJ0 2/20 0.65
TSHR P16473 2/20 0.65
MAPK1 P28482 1/20 0.65
CYP1A2 P05177 3/20 0.63
CYP3A4 P08684 3/20 0.63
CYP2C8 P10632 2/20 0.63
CYP2C9 P11712 2/20 0.63
CYP2B6 P20813 2/20 0.63
CYP2C19 P33261 2/20 0.63
LMNA P02545 2/20 0.63
GLA P06280 1/20 0.63
MTNR1A P48039 1/20 0.62
MTNR1B P49286 1/20 0.62
GAA P10253 2/20 0.61
ALDH1A1 P00352 1/20 0.61
NFKB1 P19838 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
PTPN1 P18031 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zingerone SCHEMBL14763994 1.00 ALOX5 (0.74) ALOX5OR51E2TAAR1TSHRMAPK1
Zingerone SCHEMBL119051 1.00 ALOX5 (0.74) ALOX5OR51E2TAAR1TSHRMAPK1
Zingerone SCHEMBL29828498 1.00 ALOX5 (0.74) ALOX5OR51E2TAAR1TSHRMAPK1
Zingerone SCHEMBL28865670 0.93 ALOX5 (0.65) ALOX5OR51E2TAAR1TSHRMAPK1
Zingerone SCHEMBL27825673 0.91 ALOX5 (0.63) ALOX5OR51E2TAAR1TSHRMAPK1
SCHEMBL27488164 0.90 MTNR1A (0.68) ALOX5OR51E2TAAR1TSHRMAPK1
Zingerone SCHEMBL11906310 0.89 ALOX5 (0.74) ALOX5OR51E2TAAR1TSHRMAPK1
SCHEMBL28355932 0.88 ALOX5 (0.88) ALOX5OR51E2TAAR1TSHRMAPK1
SCHEMBL2467651 0.88 ALOX5 (0.86) ALOX5OR51E2TAAR1TSHRMAPK1
SCHEMBL29986264 0.88 ALOX5 (0.86) ALOX5OR51E2TAAR1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031287-A A composition containing zingibenone A with repairing and anti-wrinkle effects and its preparation method 大连双迪科技股份有限公司 2026-05-15 CN claimed
EP-3463588-B1 USE OF GINGER ROOT CO2 EXTRACT SYMRISE AG (DE) 2025-09-17 EP claimed
CN-119968452-A Perfume mixture (VI) 西姆莱斯股份公司 2025-05-09 CN claimed
CN-119790128-A Perfume mixture (III) 西姆莱斯股份公司 2025-04-08 CN claimed
US-20250108023-A1 Products for Masking Bitterness The Third People's Hospital of Henan Province (CN) 2025-04-03 US claimed
CN-115427421-B 3' -Ketoglycoside compounds for slow release of volatile alcohols 格莱克科学有限公司 2025-04-01 CN claimed
CN-119317696-A Perfume mixture (V) 西姆莱斯股份公司 2025-01-14 CN claimed
CN-119317695-A Perfume mixture (V) 西姆莱斯股份公司 2025-01-14 CN claimed
CN-118829416-A Composition (III) 西姆莱斯股份公司 2024-10-22 CN claimed
EP-4444095-A1 ARTHROPOD CONTROL COMPOSITIONS Firmenich SA (CH) 2024-10-16 EP claimed
WO-2023112966-A1 SPRAY DEVICE AND AIR TREATMENT DEVICE ダイキン工業株式会社 2023-06-22 WO claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
WO-2023046730-A1 COSMETIC COMPOSITIONS CONTAINING CANNABIDIOL AND ZINGIBER EXTRACT BIONORICA SE (DE) 2023-03-30 WO claimed
US-11602496-B2 Use of gingerone or derivatives thereof for reducing or delaying the signs of skin ageing L'OREAL (FR) 2023-03-14 US claimed
WO-2023031860-A1 COMPOSITIONS, KITS, AND METHODS TO PROVIDE SYNERGISTIC AND/OR ADDITIVE EFFECTS FROM COMPRISED INGREDIENTS FOR THE PREVENTION, TREATMENT AND MANAGEMENT OF NAUSEA AND VOMITING. PATEL, Natvarlal Hargovinddas (IN) 2023-03-09 WO claimed
WO-2023031861-A1 COMPOSITIONS, KITS, AND METHODS FOR TREATMENT OF NAUSEA AND VOMITING PATEL, Natvarlal Hargovinddas (IN) 2023-03-09 WO claimed
WO-2023031779-A1 COMPOSITIONS, KITS, AND METHODS TO PROVIDE SYNERGISTIC AND/OR ADDITIVE EFFECTS FROM COMPRISED INGREDIENTS FOR THE PREVENTION, TREATMENT AND MANAGEMENT OF NAUSEA AND VOMITING PATEL, Natvarlal Hargovinddas (IN) 2023-03-09 WO claimed
EP-4106822-A1 BAD-ODOR CONTROL USING ENCAPSULATION TECHNOLOGIES CONTAINING NEUTRALIZING AGENT Henkel AG & Co. KGaA (DE) 2022-12-28 EP claimed
EP-4103576-A1 3'-KETOGLYCOSIDE COMPOUND FOR THE SLOW RELEASE OF A VOLATILE ALCOHOL Glycoscience, S.L. (ES) 2022-12-21 EP claimed
EP-4011352-A1 NEW COSMETICS SOLVENTS BASED ON THREE DIFFERENT COMPONENTS Beiersdorf AG (DE) 2022-06-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11602496-B2 Use of gingerone or derivatives thereof for reducing or delaying the signs of skin ageing CYP11B1, AKR1C3, GLA ALOX5 32/4885OR51E2 1514/4885TAAR1 2663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.