Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502082 | 1.00 | L3MBTL1 (0.53) | L3MBTL1TDP1MAPTTHRATHRB | |
| SCHEMBL10263254 | 0.95 | L3MBTL1 (0.50) | L3MBTL1TDP1MAPTTHRATHRB | |
| SCHEMBL19461858 | 0.84 | L3MBTL1 (0.50) | L3MBTL1TDP1MAPTALDH1A1MAPK1 | |
| SCHEMBL6594630 | 0.83 | L3MBTL1 (0.49) | L3MBTL1TDP1MAPTALDH1A1MAPK1 | |
| SCHEMBL18688617 | 0.82 | PDE4D (0.50) | L3MBTL1TDP1MAPTALDH1A1ATM | |
| SCHEMBL12129028 | 0.82 | KDM4E (0.59) | L3MBTL1TDP1MAPTALDH1A1MAPK1 | |
| SCHEMBL8975125 | 0.81 | THRA (0.53) | THRATHRBSMPD1PRSS1L3MBTL4 | |
| SCHEMBL17848587 | 0.81 | L3MBTL1 (0.46) | L3MBTL1TDP1MAPTALDH1A1MAPK1 | |
| SCHEMBL9631985 | 0.81 | KCNH2 (0.54) | L3MBTL1TDP1MAPTALDH1A1MAPK1 | |
| SCHEMBL6740315 | 0.81 | L3MBTL1 (0.50) | L3MBTL1TDP1MAPTTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947352-A1 | COMPLEMENT MODULATORS AND RELATED METHODS | RA Pharmaceuticals, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |