SCHEMBL29378886

SCHEMBL29378886

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 2/20 0.56
▸ BACE1 P56817 6/20 0.52
▸ NTSR2 O95665 3/20 0.52
▸ NTSR1 P30989 3/20 0.52
▸ BACE2 Q9Y5Z0 2/20 0.51
▸ OPRM1 P35372 2/20 0.49
▸ OPRD1 P41143 2/20 0.49
▸ NPY1R P25929 1/20 0.49
▸ NPY2R P49146 1/20 0.49
▸ NPY4R P50391 1/20 0.49
▸ OPRK1 P41145 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29972923 0.91 NAALAD2 (0.53) BACE1NTSR2NTSR1BACE2
SCHEMBL31482342 0.89 FOLH1 (0.57) NTSR2NTSR1OPRM1OPRD1NPY1R
SCHEMBL29369469 0.89 FOLH1 (0.57) NTSR2NTSR1OPRM1OPRD1NPY1R
SCHEMBL29531691 0.88 NPY4R (0.59) BACE1BACE2OPRD1NPY1RNPY2R
SCHEMBL31226890 0.88 KISS1R (0.54) KISS1RBACE1NTSR2NTSR1BACE2
SCHEMBL31696338 0.88 BACE1 (0.67) KISS1RBACE1BACE2
SCHEMBL18905180 0.87 BACE1 (0.52) KISS1RBACE1NTSR2NTSR1BACE2
SCHEMBL29857400 0.87 ACE (0.51) KISS1RBACE1BACE2OPRM1OPRD1
SCHEMBL29458786 0.87 ACE (0.51) KISS1RBACE1BACE2OPRM1OPRD1
SCHEMBL11886068 0.87 ACE (0.51) KISS1RBACE1BACE2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209054-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2024-06-27 — — US claimed
US-11814417-B2 GIP agonist compounds and methods ZEALAND PHARMA A/S (DK) 2023-11-14 — — US claimed
US-20220041676-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2022-02-10 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209054-A1 GIP AGONIST COMPOUNDS AND METHODS GIPR, GLP1R, GPR119 KISS1R 129/4885BACE1 3779/4885NTSR2 52/4885
US-11814417-B2 GIP agonist compounds and methods GIPR, GLP1R, GPR119 KISS1R 129/4885BACE1 3779/4885NTSR2 52/4885
US-20220041676-A1 GIP AGONIST COMPOUNDS AND METHODS GIPR, GLP1R, GPR119 KISS1R 129/4885BACE1 3779/4885NTSR2 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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