Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013725 | 1.00 | L3MBTL1 (0.51) | L3MBTL1HTR6EPHX1PDE10AADAM17 | |
| SCHEMBL26672944 | 0.90 | HTR6 (0.50) | L3MBTL1HTR6EPHX1PDE10AADAM17 | |
| SCHEMBL23218891 | 0.90 | HTR6 (0.55) | L3MBTL1HTR6EPHX1PDE10ACCNB2 | |
| SCHEMBL29591721 | 0.90 | HTR6 (0.55) | L3MBTL1HTR6EPHX1PDE10ACCNB2 | |
| SCHEMBL16727042 | 0.89 | L3MBTL1 (0.47) | L3MBTL1HTR6EPHX1PDE10AADAM17 | |
| SCHEMBL22919485 | 0.86 | L3MBTL1 (0.55) | L3MBTL1HTR6EPHX1PDE10AADAM17 | |
| SCHEMBL29352824 | 0.85 | L3MBTL1 (0.45) | L3MBTL1HTR6EPHX1PDE10AADAM17 | |
| SCHEMBL29077852 | 0.85 | HTR6 (0.48) | L3MBTL1HTR6EPHX1PDE10AADAM17 | |
| SCHEMBL15777230 | 0.85 | L3MBTL1 (0.45) | L3MBTL1HTR6EPHX1PDE10AADAM17 | |
| SCHEMBL26683954 | 0.85 | L3MBTL1 (0.56) | L3MBTL1HTR6EPHX1PDE10AADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947352-A1 | COMPLEMENT MODULATORS AND RELATED METHODS | RA Pharmaceuticals, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |