SCHEMBL29379380

SCHEMBL29379380

CC(C)(C)n1nc(-c2cccc3ccccc23)c2c(N)ncnc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 13/20 1.00
ABL1 P00519 7/20 1.00
PRKD3 O94806 5/20 1.00
PRKD2 Q9BZL6 5/20 1.00
PRKD1 Q15139 4/20 1.00
RIPK2 O43353 4/20 1.00
FYN P06241 4/20 1.00
CSK P41240 3/20 1.00
MAPK8 P45983 3/20 1.00
CSNK1D P48730 3/20 1.00
CDK2 P24941 2/20 1.00
CAMK2A Q9UQM7 2/20 1.00
PRKCE Q02156 1/20 1.00
PIK3CD O00329 1/20 0.64
PIK3CA P42336 1/20 0.64
PIK3CB P42338 1/20 0.64
PIK3CG P48736 1/20 0.64
PRKDC P78527 1/20 0.64
PRKACA P17612 3/20 0.64
CSNK1A1 P48729 3/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173288 1.00 SRC (1.00) SRCABL1PRKD3PRKD2PRKD1
SCHEMBL29389632 1.00 SRC (1.00) SRCABL1PRKD3PRKD2PRKD1
Hydrochloric Acid SCHEMBL7037036 0.99 SRC (0.98) SRCABL1PRKD3PRKD2PRKD1
Hydrochloric Acid SCHEMBL30682158 0.99 SRC (0.98) SRCABL1PRKD3PRKD2PRKD1
Hydrochloric Acid SCHEMBL31031035 0.99 SRC (0.98) SRCABL1PRKD3PRKD2PRKD1
SCHEMBL12551746 0.85 SRC (0.74) SRCABL1PRKD3PRKD2PRKD1
SCHEMBL13019875 0.84 SRC (0.73) SRCABL1PRKD3PRKD2PRKD1
SCHEMBL12551755 0.84 SRC (0.73) SRCABL1PRKD3PRKD2PRKD1
SCHEMBL3611430 0.84 SRC (0.72) SRCABL1PRKD3PRKD2PRKD1
SCHEMBL12551780 0.82 SRC (0.70) SRCABL1PRKD3PRKD2PRKD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2026-04-07 US claimed
WO-2025202361-A1 ANTI-GPC1 ANTIBODIES AND USES THEREOF ADCENDO APS (DK) 2025-10-02 WO claimed
US-20250302977-A1 ANTIBODY-DRUG CONJUGATES COMPRISING HUMANIZED ANTIBODIES TARGETING UROKINASE TYPE PLASMINOGEN ACTIVATOR RECEPTOR ASSOCIATED PROTEIN (UPARAP) RIGSHOSPITALET (DK) 2025-10-02 US claimed
US-20250262167-A1 COMPOUNDS, TARGETS AND PATHWAYS FOR MACROPHAGE MODULATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2025-08-21 US claimed
WO-2025099152-A1 ANTIBODIES AND MOLECULAR CONJUGATES THEREOF TARGETING UPAR RIGSHOSPITALET (DK) 2025-05-15 WO claimed
CN-119072322-A Methods and compositions for preventing or treating myopia 坪田实验室股份有限公司 2024-12-03 CN claimed
US-20240358678-A1 METHODS AND COMPOSITIONS FOR ENHANCING CHEMOTHERAPEUTIC DRUG UPTAKE INTO BRAIN TUMORS BROWN UNIVERSITY 2024-10-31 US claimed
WO-2024182413-A1 THERAPEUTIC METHODS SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) 2024-09-06 WO claimed
CN-118141921-A Use of CAMK2 inhibitors for the preparation of a medicament for reducing resistance to EGFR-driven cancers 四川大学 2024-06-07 CN claimed
EP-4363447-A1 ANTIBODY-DRUG CONJUGATES COMPRISING HUMANIZED ANTIBODIES TARGETING UROKINASE TYPE PLASMINOGEN ACTIVATOR RECEPTOR ASSOCIATED PROTEIN (UPARAP) Rigshospitalet (DK) 2024-05-08 EP claimed
US-20230310380-A1 METHODS, DEVICES, AND SYSTEMS FOR TREATING LENS PROTEIN AGGREGATION DISEASES GLAZIER ALAN NEIL (US) 2023-10-05 US claimed
EP-4213901-A1 COMPOUNDS, TARGETS AND PATHWAYS FOR MACROPHAGE MODULATION Massachusetts Institute of Technology (US) 2023-07-26 EP claimed
CN-116390760-A Compositions and methods for increasing sensitivity of cancer cells to alternating electric fields 诺沃库勒有限责任公司 2023-07-04 CN claimed
CN-116368384-A Compounds, targets and pathways for macrophage modulation 麻省理工学院 2023-06-30 CN claimed
EP-4188380-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS Novocure GmbH (CH) 2023-06-07 EP claimed
WO-2023275112-A1 ANTIBODY-DRUG CONJUGATES COMPRISING HUMANIZED ANTIBODIES TARGETING UROKINASE TYPE PLASMINOGEN ACTIVATOR RECEPTOR ASSOCIATED PROTEIN (UPARAP) RIGSHOSPITALET (DK) 2023-01-05 WO claimed
US-20220096818-A1 Compositions And Methods For Increasing Cancer Cell Sensitivity To Alternating Electric Fields BIOPHARMA CREDIT PLC (GB) 2022-03-31 US claimed
WO-2022060466-A1 COMPOUNDS, TARGETS AND PATHWAYS FOR MACROPHAGE MODULATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-03-24 WO claimed
US-20220087950-A1 COMPOUNDS, TARGETS AND PATHWAYS FOR MACROPHAGE MODULATION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-03-24 US claimed
WO-2022029628-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2022-02-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358678-A1 METHODS AND COMPOSITIONS FOR ENHANCING CHEMOTHERAPEUTIC DRUG UPTAKE INTO BRAIN TUMORS SLC19A1, SLC5A7, FABP7 SRC 894/4885ABL1 971/4885PRKD3 3178/4885
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields PTK2, GSK3B, MTOR SRC 10/4885ABL1 751/4885PRKD3 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.