Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALPI | P09923 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | ALPL | P05186 | 2/20 | 0.46 |
| ▸ | ALPG | P10696 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657894 | 1.00 | POLB (0.48) | POLBGAAKDM4EALPIMAPT | |
| SCHEMBL7550704 | 0.75 | CYP19A1 (0.49) | CYP19A1 | |
| SCHEMBL6050215 | 0.75 | MAOB (0.43) | ALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL2743637 | 0.75 | SLC6A2 (0.40) | ATMALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL2743600 | 0.75 | MAOB (0.43) | CYP19A1ALDH1A1 | |
| SCHEMBL2743842 | 0.75 | MAOB (0.43) | ALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL12673930 | 0.74 | POLB (0.58) | POLBGAAKDM4EALPIMAPT | |
| SCHEMBL28354123 | 0.74 | TSHR (0.43) | GAAKDM4EATMCYP19A1ALDH1A1 | |
| SCHEMBL2743656 | 0.74 | TSHR (0.43) | GAAKDM4EATMCYP19A1ALDH1A1 | |
| SCHEMBL2743638 | 0.73 | HSD11B1 (0.46) | MAPTCYP19A1ALDH1A1TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946286-A1 | METHODS FOR CONTINUOUS EXTRACTION AND PURIFICATION OF A UNIQUE FLAVAN-3-OL EXTRACT FROM IMMATURE WHOLE GRAPE CLUSTERS AND COMPOSITIONS THEREOF | E. & J. Gallo Winery (US) | 2022-02-09 | — | — | EP | disclosed |