SCHEMBL7550704

SCHEMBL7550704

O=C1CCCCC(c2cccc(O)c2)O1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.49
DRD3 P35462 2/20 0.42
DRD2 P14416 1/20 0.42
AKT1 P31749 1/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1331244 0.80 KDM4E (0.42) CYP19A1
SCHEMBL15883776 0.80 KDM4E (0.42) CYP19A1
SCHEMBL2743638 0.77 HSD11B1 (0.46) CYP19A1DRD3DRD2
SCHEMBL2743656 0.75 TSHR (0.43) CYP19A1
SCHEMBL28354123 0.75 TSHR (0.43) CYP19A1
SCHEMBL29380654 0.75 POLB (0.48) CYP19A1
SCHEMBL20657894 0.75 POLB (0.48) CYP19A1
SCHEMBL2744062 0.74 HTR1A (0.47) DRD3DRD2
SCHEMBL10698757 0.74 LMNA (0.53) CYP19A1
SCHEMBL28408881 0.73 HDAC4 (0.42) HDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944679-B1 COATING AGENT- THE MANUFACTURE AND USE THEREOF DU PONT (US) 2002-07-03 EP disclosed
EP-0904310-B1 BINDER AND COATING AGENT COMPOSITION AND ITS USE IN MULTICOAT PAINTING DU PONT (US) 2001-09-19 EP disclosed
US-6268021-B1 CROSSLINKING HERBERTS GMBH (DE) 2001-07-31 US disclosed
US-6200639-B1 BINDER LACQUER BLEND CONTAINING SOLVENT, WATER, PIGMENTS, FILLERS HERBERTS GMBH., KG (DE) 2001-03-13 US disclosed
EP-0797643-B1 BINDER COMPOSITION, A COATING AGENT CONTAINING SAID BINDER COMPOSITION, ITS PRODUCTION AND USE HERBERTS & CO GMBH (DE) 1999-01-13 EP disclosed
EP-0598280-B1 Binder composition, coating containing it, its preparation and its use HERBERTS & CO GMBH (DE) 1998-09-16 EP disclosed
EP-0603561-B1 Binders containing polysiloxane, their preparation, coating compositions containing them and their use HERBERTS & CO GMBH (DE) 1998-08-05 EP disclosed
US-5739216-A Binder composition, coating compositions containing this binder composition, production and use thereof HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-04-14 US disclosed
US-5710208-A LACQUERS IN AUTOMOBILES HERBERTS GMBH (DE) 1998-01-20 US disclosed
US-5686532-A MULTILAYER LACQUER COATINGS USED IN AUTOMOBILES HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1997-11-11 US disclosed
EP-0597394-B1 Binder composition, coating containing the same, manufacture and use thereof HERBERTS & CO GMBH (DE) 1997-02-12 EP disclosed
WO-1995018161-A1 BINDERS BASED ON CYCLO-OLEFINIC, IF REQUIRED PEROXYGENATED COPOLYMERS, THEIR PREPARATION, COATING MEDIA CONTAINING THE SAME AND THEIR USE Herberts Gesellschaft mit beschränkter Haftung (DE) 1995-07-06 WO disclosed
US-5426151-A Dirt-repellant, antigraffiti coating HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-06-20 US disclosed
EP-0603561-A1 Binders containing polysiloxane, their preparation, coating containing them and their use Herberts Gesellschaft mit beschränkter Haftung (DE) 1994-06-29 EP disclosed
EP-0598280-A2 Binder composition, coating containing it, its preparation and its use Herberts Gesellschaft mit beschränkter Haftung (DE) 1994-05-25 EP disclosed
EP-0597394-A2 Binder composition, coating containing the same, manufacture and use thereof Herberts Gesellschaft mit beschränkter Haftung (DE) 1994-05-18 EP disclosed
US-5082922-A Decyclization, esterification, amidation, etherification THE VALSPAR CORPORATION (US) 1992-01-21 US disclosed
EP-0439526-A4 MODIFIED-ACRYLATE POLYMERS AND COATING COMPOSITIONS MADE THEREFROM 1991-12-18 EP disclosed
EP-0439526-A1 MODIFIED-ACRYLATE POLYMERS AND COATING COMPOSITIONS MADE THEREFROM THE VALSPAR CORPORATION (US) 1991-08-07 EP disclosed
WO-1990003991-A1 MODIFIED-ACRYLATE POLYMERS AND COATING COMPOSITIONS MADE THEREFROM THE VALSPAR CORPORATION (US) 1990-04-19 WO disclosed