Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22500189 | 1.00 | MAPT (0.38) | MAPTPLA2G10HPGDRAB9ANPC1 | |
| SCHEMBL22499974 | 0.84 | MAPK8 (0.39) | MAPTKDM4EMEN1KMT2A | |
| SCHEMBL29385131 | 0.81 | MAOB (0.41) | HPGDRAB9ANPC1CYP3A4SMN1; SMN2 | |
| SCHEMBL29384893 | 0.79 | UBE2N (0.37) | L3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL28666652 | 0.79 | UBE2N (0.37) | L3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL15353532 | 0.74 | IMPDH2 (0.42) | MAPTHPGDCYP1A2CYP2C9CDK8 | |
| SCHEMBL12906309 | 0.72 | CDK8 (0.42) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL469899 | 0.72 | GSK3B (0.46) | HPGDCYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL28682257 | 0.71 | HSP90AA1 (0.42) | MAPTHPGDRAB9ANPC1CYP1A2 | |
| SCHEMBL28679753 | 0.71 | HSP90AA1 (0.42) | MAPTHPGDRAB9ANPC1CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3949731-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE | Nissan Chemical Corporation (JP) | 2022-02-09 | — | — | EP | disclosed |