Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 2/20 | 0.44 |
| ▸ | CCND1 | P24385 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15064066 | 0.83 | GSK3B (0.49) | GSK3BCCNT1CDK9CDK4CCND1 | |
| SCHEMBL15086662 | 0.80 | GSK3B (0.46) | GSK3BCCNT1CDK9CDK4CCND1 | |
| SCHEMBL469897 | 0.79 | GSK3B (0.45) | GSK3BCCNT1CDK9CDK4CCND1 | |
| SCHEMBL12906309 | 0.79 | CDK8 (0.42) | ALDH1A1KDM4EHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL15353202 | 0.77 | SIRT2 (0.46) | GSK3BCCNT1CDK9KDRCDK4 | |
| SCHEMBL15353532 | 0.72 | IMPDH2 (0.42) | MEN1ALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL22500189 | 0.72 | MAPT (0.38) | MEN1ALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL29382005 | 0.72 | MAPT (0.38) | MEN1ALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL513464 | 0.71 | ESRRA (0.36) | MEN1ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL18858379 | 0.71 | PDE4A (0.64) | GSK3BCCNT1CDK9CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |