Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033311 | 0.89 | HDAC4 (0.50) | HDAC6HDAC8HDAC4HDAC2 | |
| SCHEMBL22531170 | 0.85 | CPT2 (0.47) | HDAC6HDAC8HDAC1HDAC4HDAC2 | |
| SCHEMBL29381493 | 0.85 | HDAC4 (0.65) | HDAC6HDAC1HDAC4 | |
| SCHEMBL29381942 | 0.85 | HDAC4 (0.65) | HDAC6HDAC8HDAC1HDAC4HDAC2 | |
| SCHEMBL29381433 | 0.83 | HDAC4 (0.65) | HDAC6HDAC8HDAC1HDAC4HDAC2 | |
| SCHEMBL21033488 | 0.83 | HDAC4 (0.53) | HDAC6HDAC8HDAC1HDAC4HDAC2 | |
| SCHEMBL30845754 | 0.82 | TGFBR1 (0.48) | TGFBR1EGLN1 | |
| SCHEMBL29381684 | 0.82 | HDAC4 (0.49) | HDAC6HDAC8HDAC1HDAC4 | |
| SCHEMBL29379315 | 0.82 | HDAC4 (0.48) | HDAC6HDAC1HDAC4 | |
| SCHEMBL29381838 | 0.81 | HDAC4 (0.69) | HDAC6HDAC8HDAC1HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542523-B | Heterocyclic compounds as PRMT5 inhibitors | 朱比连特埃皮斯科瑞有限责任公司 | 2024-03-29 | — | — | CN | claimed |
| EP-3953353-A1 | NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI | PI Industries Ltd. (IN) | 2022-02-16 | — | — | EP | claimed |
| CN-111542523-B | Heterocyclic compounds as PRMT5 inhibitors | 朱比连特埃皮斯科瑞有限责任公司 | 2024-03-29 | — | — | CN | disclosed |