Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25370121 | 0.77 | TGFBR1 (0.35) | TGFBR1 | |
| SCHEMBL30428787 | 0.75 | EPHA2 (0.47) | — | |
| SCHEMBL25663602 | 0.75 | EPHA2 (0.47) | — | |
| SCHEMBL29382633 | 0.71 | LRRK2 (0.36) | TGFBR1KDM4E | |
| SCHEMBL30938807 | 0.70 | EGFR (0.41) | TGFBR1KDM4E | |
| SCHEMBL29382623 | 0.69 | KDM4E (0.41) | KDM4E | |
| SCHEMBL30420076 | 0.68 | TGFBR1 (0.36) | TGFBR1 | |
| SCHEMBL31193354 | 0.67 | SIGMAR1 (0.39) | — | |
| SCHEMBL25215331 | 0.66 | EPHA2 (0.45) | — | |
| SCHEMBL29382383 | 0.65 | POLB (0.33) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033410-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |