Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALPG | P10696 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27517299 | 0.89 | ALDH1A1 (0.45) | ALDH1A1LOXL2HTTSMN1; SMN2ALPG | |
| SCHEMBL31366315 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LOXL2HTTSMN1; SMN2ALPG | |
| SCHEMBL6882189 | 0.82 | ALDH1A1 (0.57) | ALDH1A1LOXL2SMN1; SMN2 | |
| SCHEMBL8552853 | 0.80 | CYP3A4 (0.52) | ALDH1A1LOXL2HTTSMN1; SMN2ALPG | |
| SCHEMBL11365248 | 0.79 | CYP1A2 (0.53) | ALDH1A1HTTSMN1; SMN2ALPGALPL | |
| SCHEMBL978161 | 0.77 | TAAR1 (0.47) | ALDH1A1CYP3A4CYP2D6HIF1AKMT2A | |
| SCHEMBL7188310 | 0.77 | TAAR1 (0.47) | CYP3A4CYP2D6HIF1AMEN1KMT2A | |
| SCHEMBL18392033 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HTTSMN1; SMN2ALPGALPL | |
| SCHEMBL7979576 | 0.75 | P2RX7 (0.38) | ALDH1A1HTTCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1833158 | 0.75 | CYP1A2 (0.53) | ALDH1A1HTTSMN1; SMN2ALPGALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230298145-A1 | MASSIVELY PARALLEL AMPLITUDE-ONLY OPTICAL PROCESSING SYSTEM AND METHODS FOR MACHINE LEARNING | THE GEORGE WASHINGTON UNIVERSITY | 2023-09-21 | — | — | US | disclosed |
| WO-2022031982-A1 | MASSIVELY PARALLEL AMPLITUDE-ONLY OPTICAL PROCESSING SYSTEM AND METHODS FOR MACHINE LEARNING | THE GEORGE WASHINGTON UNIVERSITY (US) | 2022-02-10 | — | — | WO | disclosed |