Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 7/20 | 0.55 |
| ▸ | NOS3 | P29474 | 2/20 | 0.55 |
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163051 | 1.00 | MAPK10 (0.55) | MAPK10NOS3NOS2MAOAALDH1A1 | |
| Hydrochloric Acid SCHEMBL27495714 | 0.98 | MAPK10 (0.54) | MAPK10NOS3NOS2MAOAALDH1A1 | |
| SCHEMBL5348300 | 0.89 | NOS3 (0.58) | MAPK10NOS3NOS2MAOAGABRA1 | |
| SCHEMBL28542282 | 0.85 | MAPK10 (0.50) | MAPK10NOS3NOS2MAOAALDH1A1 | |
| SCHEMBL29498358 | 0.85 | MAPK10 (0.55) | MAPK10NOS3NOS2MAOAALDH1A1 | |
| SCHEMBL13805616 | 0.85 | NOS3 (0.49) | MAPK10NOS3NOS2MAOAALDH1A1 | |
| SCHEMBL11269191 | 0.85 | MAPK10 (0.55) | MAPK10NOS3NOS2MAOAALDH1A1 | |
| SCHEMBL6718892 | 0.85 | NOS3 (0.58) | MAPK10NOS3NOS2MAOAALDH1A1 | |
| SCHEMBL21063722 | 0.85 | CA1 (0.52) | MAPK10NOS3NOS2MAOAALDH1A1 | |
| SCHEMBL30965936 | 0.85 | CA1 (0.52) | MAPK10NOS3NOS2MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552116-A | Preparation method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline | 浙江工业大学 | 2025-03-04 | — | — | CN | claimed |
| CN-116218804-A | Imine reductase mutant and method for preparing (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline by reduction thereof | 迪嘉药业集团股份有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-112142663-B | Synthesis method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline | 中山奕安泰医药科技有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-119552116-B | Preparation method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline | 浙江工业大学 | 2025-11-11 | — | — | CN | disclosed |
| CN-119552116-A | Preparation method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline | 浙江工业大学 | 2025-03-04 | — | — | CN | disclosed |
| CN-119552116-A | Preparation method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline | 浙江工业大学 | 2025-03-04 | — | — | CN | disclosed |
| CN-118146154-A | Method for synergistic catalysis of selective oxidative dehydrogenation of tetrahydroisoquinoline | 西安石油大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-114195713-B | Method for synthesizing dihydroisoquinoline by catalyzing selective dehydrogenation of tetrahydroisoquinoline | 广东众源药业有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116218804-A | Imine reductase mutant and method for preparing (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline by reduction thereof | 迪嘉药业集团股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116218804-A | Imine reductase mutant and method for preparing (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline by reduction thereof | 迪嘉药业集团股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-111303145-B | Small molecule fluorescent probe and application thereof in chromosome analysis and cytogenetics | 陈斯杰 | 2023-02-28 | — | — | CN | disclosed |
| CN-112500345-B | Synthetic method of alpha-cyano quaternary carbon substituted tetrahydroisoquinoline compound | 西安石油大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-112142663-B | Synthesis method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline | 中山奕安泰医药科技有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-112142663-B | Synthesis method of (S) -1-phenyl-1, 2,3, 4-tetrahydroisoquinoline | 中山奕安泰医药科技有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-111621805-B | Method for preparing 3, 4-dihydroisoquinoline by electrocatalytic selective dehydrogenation | 天津大学 | 2022-02-18 | — | — | CN | disclosed |