Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | FGFR1 | P11362 | 12/20 | 0.53 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15413235 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2FGFR1FGFR2 | |
| Hydrochloric Acid SCHEMBL28010166 | 0.99 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2FGFR1FGFR2 | |
| SCHEMBL24335187 | 0.92 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2FGFR1FGFR2 | |
| SCHEMBL29385006 | 0.87 | FGFR1 (0.55) | KDM4EALDH1A1SMN1; SMN2FGFR1FGFR2 | |
| SCHEMBL16667808 | 0.87 | FGFR1 (0.55) | KDM4EALDH1A1SMN1; SMN2FGFR1FGFR2 | |
| SCHEMBL16668439 | 0.84 | FGFR1 (0.52) | KDM4EALDH1A1SMN1; SMN2FGFR1FGFR2 | |
| SCHEMBL31647846 | 0.84 | FGFR1 (0.59) | KDM4EALDH1A1SMN1; SMN2FGFR1FGFR2 | |
| SCHEMBL29386366 | 0.84 | FGFR1 (0.52) | KDM4EALDH1A1SMN1; SMN2FGFR1FGFR2 | |
| SCHEMBL31647808 | 0.81 | FGFR1 (0.49) | KDM4EALDH1A1SMN1; SMN2FGFR1FGFR2 | |
| SCHEMBL1010778 | 0.80 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028491-B | Fibroblast growth factor receptor inhibitors | 缆图药品公司 | 2022-02-11 | — | — | CN | disclosed |