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Vinepidine

Vinepidine

SCHEMBL29385187

CC[C@H]1C[C@@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C(=O)OC)(c3cc4c(cc3OC)N(C=O)[C@H]3[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]5(CC)C=CCN6CC[C@]43[C@@H]65)C2)C1

nearest known ligand 0.85

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 6/20 0.85
▸ HIF1A Q16665 5/20 0.85
▸ CYP3A4 P08684 5/20 0.85
▸ TUBB4A P04350 5/20 0.85
▸ TUBB P07437 5/20 0.85
▸ TUBA3C P0DPH7 5/20 0.85
▸ TUBA1B P68363 5/20 0.85
▸ TUBA4A P68366 5/20 0.85
▸ TUBB4B P68371 5/20 0.85
▸ TUBB3 Q13509 5/20 0.85
▸ TUBB2A Q13885 5/20 0.85
▸ TUBB8 Q3ZCM7 5/20 0.85
▸ TUBA3E Q6PEY2 5/20 0.85
▸ TUBA1A Q71U36 5/20 0.85
▸ TUBA1C Q9BQE3 5/20 0.85
▸ TUBB6 Q9BUF5 5/20 0.85
▸ TUBB2B Q9BVA1 5/20 0.85
▸ TUBB1 Q9H4B7 5/20 0.85
▸ ALOX15 P16050 4/20 0.85
▸ TP53 P04637 3/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vinepidine SCHEMBL285304 1.00 LMNA (0.85) LMNAHIF1ACYP3A4TUBB4ATUBB
Vinepidine SCHEMBL29376135 0.98 MAPT (0.85) LMNAHIF1ACYP3A4TUBB4ATUBB
Vinepidine SCHEMBL4076 0.98 MAPT (0.85) LMNAHIF1ACYP3A4TUBB4ATUBB
Roseamine SCHEMBL30368397 0.94 MAPT (0.85) LMNAHIF1ACYP3A4TUBB4ATUBB
Roseamine SCHEMBL10059227 0.94 MAPT (0.85) LMNAHIF1ACYP3A4TUBB4ATUBB
Vincristine SCHEMBL18402663 0.92 LMNA (1.00) LMNAHIF1ACYP3A4TUBB4ATUBB
Vincristine SCHEMBL4769981 0.92 LMNA (1.00) LMNAHIF1ACYP3A4TUBB4ATUBB
Vincristine SCHEMBL19522762 0.92 LMNA (1.00) LMNAHIF1ACYP3A4TUBB4ATUBB
Vincristine SCHEMBL15866613 0.92 LMNA (1.00) LMNAHIF1ACYP3A4TUBB4ATUBB
Vincristine SCHEMBL15474330 0.92 LMNA (1.00) LMNAHIF1ACYP3A4TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3441089-B1 TREATMENT METHODS USING ADENOVIRUS VASCULAR BIOGENICS LTD (IL) 2022-12-14 — — EP claimed
CN-111886499-B Method for detecting RAD51 focus in tumor cells 瓦尔希伯伦私人肿瘤研究基金会 2024-10-29 — — CN disclosed
CN-112996854-B High purity PEG lipids and uses thereof 摩登纳特斯有限公司 2024-08-30 — — CN disclosed
CN-115851834-A NSG mice deficient in class I and class II MHC 杰克逊实验室 2023-03-28 — — CN disclosed
CN-114302877-A Quinazolinyl compounds and methods of use 基因泰克公司 2022-04-08 — — CN disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 — — US disclosed