Roseamine

Roseamine

SCHEMBL30368397

CC[C@@H]1C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C(=O)OC)(c3cc4c(cc3OC)N(C)[C@H]3[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]5(CC)C=CCN6CC[C@]43[C@@H]65)C2)C1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.85
MEN1 O00255 6/20 0.85
KMT2A Q03164 6/20 0.85
LMNA P02545 6/20 0.85
TUBB4A P04350 5/20 0.85
TUBB P07437 5/20 0.85
TUBA3C P0DPH7 5/20 0.85
TUBA1B P68363 5/20 0.85
TUBA4A P68366 5/20 0.85
TUBB4B P68371 5/20 0.85
TUBB3 Q13509 5/20 0.85
TUBB2A Q13885 5/20 0.85
TUBB8 Q3ZCM7 5/20 0.85
TUBA3E Q6PEY2 5/20 0.85
TUBA1A Q71U36 5/20 0.85
TUBA1C Q9BQE3 5/20 0.85
TUBB6 Q9BUF5 5/20 0.85
TUBB2B Q9BVA1 5/20 0.85
TUBB1 Q9H4B7 5/20 0.85
CYP3A4 P08684 5/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Roseamine SCHEMBL10059227 1.00 MAPT (0.85) MAPTMEN1KMT2ALMNATUBB4A
SCHEMBL15941262 0.95 TUBB4A (0.79) MAPTMEN1KMT2ALMNATUBB4A
Vinepidine SCHEMBL285304 0.94 LMNA (0.85) MAPTMEN1KMT2ALMNATUBB4A
Vinepidine SCHEMBL29385187 0.94 LMNA (0.85) MAPTMEN1KMT2ALMNATUBB4A
SCHEMBL12213867 0.93 MAPT (0.83) MAPTMEN1KMT2ALMNATUBB4A
SCHEMBL12237564 0.93 MAPT (0.83) MAPTMEN1KMT2ALMNATUBB4A
SCHEMBL10018533 0.93 MAPT (0.83) MAPTMEN1KMT2ALMNATUBB4A
SCHEMBL12451436 0.93 MAPT (0.73) MAPTMEN1KMT2ALMNATUBB4A
Vinepidine SCHEMBL29376135 0.93 MAPT (0.85) MAPTMEN1KMT2ALMNATUBB4A
Vinepidine SCHEMBL4076 0.93 MAPT (0.85) MAPTMEN1KMT2ALMNATUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262706-A1 SITE-SPECIFIC PROTEIN LABELING USING OLIGONUCLEOTIDE TAGS INVITROGEN BIOSERVICES INDIA PRIVATE LIMITED (IN) 2025-12-26 WO claimed
CN-116083974-A Cobalt plating additive, cobalt plating solution and method suitable for filling cobalt into microelectronic circuit 哈尔滨工业大学 2023-05-09 CN claimed
EP-4709877-A2 METHODS AND KITS FOR DETECTING ENDOTOXIN Life Technologies Corporation (US) 2026-03-18 EP disclosed
US-20260056217-A1 NORMALIZATION METHODS LIFE TECHNOLOGIES CORP (US) 2026-02-26 US disclosed
EP-4695308-A1 ENGINEERED ANTIBODIES AND USES THEREOF Invitrogen BioServices India Private Limited (IN) 2026-02-18 EP disclosed
WO-2025262706-A1 SITE-SPECIFIC PROTEIN LABELING USING OLIGONUCLEOTIDE TAGS INVITROGEN BIOSERVICES INDIA PRIVATE LIMITED (IN) 2025-12-26 WO disclosed
EP-4594735-A2 NORMALIZATION METHODS Life Technologies Corporation (US) 2025-08-06 EP disclosed
WO-2025090132-A9 METHODS AND KITS FOR DETECTING ENDOTOXIN LIFE TECHNOLOHGIES CORPORATION (US) 2025-06-19 WO disclosed
WO-2025090132-A2 METHODS AND KITS FOR DETECTING ENDOTOXIN LIFE TECHNOLOHGIES CORPORATION (US) 2025-05-01 WO disclosed
CN-119744346-A Normalization method 生命技术公司 2025-04-01 CN disclosed
WO-2025057225-A1 ENGINEERED ANTIBODIES AND USES THEREOF INVITROGEN BIOSERVICES INDIA PRIVATE LIMITED (IN) 2025-03-20 WO disclosed
WO-2024238249-A1 EXTRACELLULAR VESICLE PROTEIN AND NUCLEIC ACID ANALYSIS Life Technologies Corporation (US) 2024-11-21 WO disclosed
CN-112279864-B Difunctional coumarin oxime ester compound and preparation and application thereof 湖北固润科技股份有限公司 2024-07-16 CN disclosed
WO-2024073291-A2 NORMALIZATION METHODS Life Technologies Corporation (US) 2024-04-04 WO disclosed
CN-115583931-B Ether-functionalized coumarin oxime ester compound and preparation and application thereof 湖北固润科技股份有限公司 2024-03-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260056217-A1 NORMALIZATION METHODS KCNQ5, KCNQ4, KCNQ2 MAPT 2356/4885MEN1 1008/4885KMT2A 3465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.