Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22499569 | 1.00 | MAPT (0.55) | MAPTSMN1; SMN2LMNAMAPK1PKM | |
| SCHEMBL22499511 | 0.95 | TBXA2R (0.53) | MAPTSMN1; SMN2LMNAMAPK1PKM | |
| SCHEMBL29383984 | 0.95 | TBXA2R (0.53) | MAPTSMN1; SMN2LMNAMAPK1PKM | |
| SCHEMBL22499485 | 0.95 | TBXA2R (0.53) | MAPTSMN1; SMN2LMNAMAPK1PKM | |
| Hydrochloric Acid SCHEMBL10892672 | 0.86 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2LMNAMAPK1PKM | |
| SCHEMBL22499562 | 0.86 | MAPT (0.63) | MAPTSMN1; SMN2LMNAMAPK1PKM | |
| SCHEMBL29382007 | 0.86 | MAPT (0.63) | MAPTSMN1; SMN2LMNAMAPK1PKM | |
| Hydrochloric Acid SCHEMBL10889762 | 0.85 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2LMNAMAPK1PKM | |
| SCHEMBL22499584 | 0.85 | CA12 (0.47) | MAPTSMN1; SMN2LMNAPKMPOLB | |
| SCHEMBL22499557 | 0.84 | ALDH1A1 (0.56) | MAPTSMN1; SMN2LMNAMAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174259-A | Modulators of intracellular chloride concentration | 意大利学院科技基金会 | 2022-03-11 | — | — | CN | claimed |
| EP-3947345-A1 | MODULATORS OF INTRACELLULAR CHLORIDE CONCENTRATION | Fondazione Istituto Italiano di Tecnologia (IT) | 2022-02-09 | — | — | EP | claimed |
| CN-114174259-A | Modulators of intracellular chloride concentration | 意大利学院科技基金会 | 2022-03-11 | — | — | CN | disclosed |
| EP-3947345-A1 | MODULATORS OF INTRACELLULAR CHLORIDE CONCENTRATION | Fondazione Istituto Italiano di Tecnologia (IT) | 2022-02-09 | — | — | EP | disclosed |