Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 11/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22499511 | 1.00 | TBXA2R (0.53) | TBXA2RSLC6A2SLC6A4DRD3CYP19A1 | |
| SCHEMBL22499485 | 1.00 | TBXA2R (0.53) | TBXA2RSLC6A2SLC6A4DRD3CYP19A1 | |
| SCHEMBL22499569 | 0.95 | MAPT (0.55) | TBXA2RSLC6A2SLC6A4DRD3CYP19A1 | |
| SCHEMBL29385190 | 0.95 | MAPT (0.55) | TBXA2RSLC6A2SLC6A4DRD3CYP19A1 | |
| SCHEMBL22499593 | 0.86 | MAPT (0.57) | TBXA2RSLC6A2SLC6A4DRD3CYP19A1 | |
| SCHEMBL29381645 | 0.86 | MAPT (0.57) | TBXA2RSLC6A2SLC6A4DRD3CYP19A1 | |
| SCHEMBL22499583 | 0.86 | MAPT (0.57) | TBXA2RSLC6A2SLC6A4DRD3CYP19A1 | |
| SCHEMBL29384824 | 0.86 | MAPT (0.57) | TBXA2RSLC6A2SLC6A4DRD3CYP19A1 | |
| SCHEMBL22499635 | 0.84 | ALDH1A1 (0.53) | TBXA2RSLC6A2SLC6A4DRD3CYP19A1 | |
| SCHEMBL22499540 | 0.84 | ALDH1A1 (0.53) | TBXA2RSLC6A2SLC6A4DRD3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174259-A | Modulators of intracellular chloride concentration | 意大利学院科技基金会 | 2022-03-11 | — | — | CN | claimed |
| EP-3947345-A1 | MODULATORS OF INTRACELLULAR CHLORIDE CONCENTRATION | Fondazione Istituto Italiano di Tecnologia (IT) | 2022-02-09 | — | — | EP | claimed |
| CN-114174259-A | Modulators of intracellular chloride concentration | 意大利学院科技基金会 | 2022-03-11 | — | — | CN | disclosed |
| EP-3947345-A1 | MODULATORS OF INTRACELLULAR CHLORIDE CONCENTRATION | Fondazione Istituto Italiano di Tecnologia (IT) | 2022-02-09 | — | — | EP | disclosed |