Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 14/20 | 0.75 |
| ▸ | USP2 | O75604 | 10/20 | 0.75 |
| ▸ | SLCO1B3 | Q9NPD5 | 4/20 | 0.67 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18969706 | 1.00 | CYP3A4 (0.75) | CYP3A4USP2SLCO1B3SLCO1B1ABCB1 | |
| SCHEMBL29574101 | 1.00 | CYP3A4 (0.75) | CYP3A4USP2SLCO1B3SLCO1B1ABCB1 | |
| SCHEMBL18324173 | 0.88 | CYP3A4 (0.63) | CYP3A4USP2SLCO1B3SLCO1B1ABCB1 | |
| SCHEMBL22899842 | 0.88 | CYP3A4 (0.69) | CYP3A4USP2SLCO1B3SLCO1B1ABCB1 | |
| Nomilin SCHEMBL691775 | 0.87 | CYP3A4 (0.80) | CYP3A4USP2SLCO1B3SLCO1B1ABCB1 | |
| Nomilin SCHEMBL29387920 | 0.87 | CYP3A4 (0.80) | CYP3A4USP2SLCO1B3SLCO1B1ABCB1 | |
| SCHEMBL10019483 | 0.86 | CYP3A4 (1.00) | CYP3A4USP2SLCO1B3SLCO1B1ABCB1 | |
| SCHEMBL22040131 | 0.84 | CYP3A4 (0.53) | CYP3A4USP2SLCO1B3SLCO1B1ABCB1 | |
| Obacunone SCHEMBL20733839 | 0.82 | CYP3A4 (0.79) | CYP3A4USP2SLCO1B3SLCO1B1ABCB1 | |
| Obacunone SCHEMBL18324167 | 0.82 | CYP3A4 (0.79) | CYP3A4USP2SLCO1B3SLCO1B1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015000-B1 | COMBINATION PRODUCT CONTAINING LIMONIN COMPOUND AND THIAZOLIDINEDIONE | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2025-01-01 | — | — | EP | claimed |
| EP-4014979-B1 | COMBINATION PRODUCT COMPRISING LIMONOIDS AND SGLT-2 INHIBITORS | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2024-09-25 | — | — | EP | claimed |
| EP-4014998-B1 | COMBINATION PRODUCT COMPRISING LIMONOID AND DPP-4 INHIBITORS | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2024-01-03 | — | — | EP | claimed |
| EP-4014999-B1 | COMBINATION PRODUCT CONTAINING LIMONIN COMPOUND AND SULFONYLUREA DRUG | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2023-11-29 | — | — | EP | claimed |
| EP-3666267-B1 | COMBINATION PRODUCT CONTAINING A LIMONOID COMPOUND AND METFORMIN | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2023-11-15 | — | — | EP | claimed |
| EP-4014978-B1 | COMBINATION PRODUCT CONTAINING A LIMONOID COMPOUND AND ACARBOSE | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2023-09-13 | — | — | EP | claimed |
| US-11679097-B2 | Combination product containing limonoid compound and biguanide compound | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2023-06-20 | — | — | US | claimed |
| US-20220313708-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND SGLT-2 INHIBITOR | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-10-06 | — | — | US | claimed |
| US-20220296615-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND SULFONYLUREA COMPOUND | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-09-22 | — | — | US | claimed |
| US-20220296566-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND ALPHA-GLUCOSIDASE INHIBITOR | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-09-22 | — | — | US | claimed |
| US-20220288046-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND THIAZOLIDINEDIONE COMPOUND | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-09-15 | — | — | US | claimed |
| US-20220226283-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND DPP-4 INHIBITOR | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-07-21 | — | — | US | claimed |
| EP-4014979-A1 | COMBINATION PRODUCT COMPRISING LIMONOIDS AND SGLT-2 INHIBITORS | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-06-22 | — | — | EP | claimed |
| EP-4014978-A1 | COMBINATION PRODUCT CONTAINING LIMONOID AND ?-GLUCOSIDASE INHIBITOR | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-06-22 | — | — | EP | claimed |
| EP-4014999-A1 | COMBINATION PRODUCT CONTAINING LIMONIN COMPOUND AND SULFONYLUREA DRUG | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-06-22 | — | — | EP | claimed |
| EP-4014998-A1 | COMBINATION PRODUCT COMPRISING LIMONOID AND DPP-4 INHIBITORS | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-06-22 | — | — | EP | claimed |
| EP-4015000-A1 | COMBINATION PRODUCT CONTAINING LIMONIN COMPOUND AND THIAZOLIDINEDIONE | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-06-22 | — | — | EP | claimed |
| CN-109381471-B | Combination product comprising limonoids and biguanides | 浙江养生堂天然药物研究所有限公司 | 2022-06-03 | — | — | CN | claimed |
| US-20220125757-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND BIGUANIDE COMPOUND | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-04-28 | — | — | US | claimed |
| US-20250213601-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES | Didenko, Kirill (US) | 2025-07-03 | — | — | US | disclosed |
| US-20250151720-A1 | METHOD FOR CONTROLLING AN INSECT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-05-15 | — | — | US | disclosed |
| EP-4015000-B1 | COMBINATION PRODUCT CONTAINING LIMONIN COMPOUND AND THIAZOLIDINEDIONE | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2025-01-01 | — | — | EP | disclosed |
| EP-4014979-B1 | COMBINATION PRODUCT COMPRISING LIMONOIDS AND SGLT-2 INHIBITORS | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2024-09-25 | — | — | EP | disclosed |
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |
| EP-4014998-B1 | COMBINATION PRODUCT COMPRISING LIMONOID AND DPP-4 INHIBITORS | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2024-01-03 | — | — | EP | disclosed |
| EP-4014999-B1 | COMBINATION PRODUCT CONTAINING LIMONIN COMPOUND AND SULFONYLUREA DRUG | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2023-11-29 | — | — | EP | disclosed |
| EP-3666267-B1 | COMBINATION PRODUCT CONTAINING A LIMONOID COMPOUND AND METFORMIN | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2023-11-15 | — | — | EP | disclosed |
| WO-2023187599-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES | DIDENKO KIRILL (MX) | 2023-10-05 | — | — | WO | disclosed |
| EP-4014978-B1 | COMBINATION PRODUCT CONTAINING A LIMONOID COMPOUND AND ACARBOSE | ZHEJIANG YANGSHENGTANG INST OF NATURAL MEDICATION CO LTD (CN) | 2023-09-13 | — | — | EP | disclosed |
| US-11679097-B2 | Combination product containing limonoid compound and biguanide compound | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2023-06-20 | — | — | US | disclosed |
| WO-2023037254-A1 | METHODS AND COMPOUNDS FOR TREATING CORONAVIRIDAE VIRUS INFECTIONS | DIDENKO KIRILL (MX) | 2023-03-16 | — | — | WO | disclosed |
| CN-115772145-A | Citrus fruit extract and preparation method and application thereof | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| US-20220313708-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND SGLT-2 INHIBITOR | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-10-06 | — | — | US | disclosed |
| US-20220296615-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND SULFONYLUREA COMPOUND | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-09-22 | — | — | US | disclosed |
| US-20220296566-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND ALPHA-GLUCOSIDASE INHIBITOR | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-09-22 | — | — | US | disclosed |
| US-20220288046-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND THIAZOLIDINEDIONE COMPOUND | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-09-15 | — | — | US | disclosed |
| CN-115024458-A | A method for improving taste and bitter taste of extract of plant of Rutaceae and Citrus | 上海龙殷生物科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| US-20220226283-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND DPP-4 INHIBITOR | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-07-21 | — | — | US | disclosed |
| EP-4014998-A1 | COMBINATION PRODUCT COMPRISING LIMONOID AND DPP-4 INHIBITORS | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-06-22 | — | — | EP | disclosed |
| EP-4014979-A1 | COMBINATION PRODUCT COMPRISING LIMONOIDS AND SGLT-2 INHIBITORS | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-06-22 | — | — | EP | disclosed |
| EP-4015000-A1 | COMBINATION PRODUCT CONTAINING LIMONIN COMPOUND AND THIAZOLIDINEDIONE | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-06-22 | — | — | EP | disclosed |
| EP-4014999-A1 | COMBINATION PRODUCT CONTAINING LIMONIN COMPOUND AND SULFONYLUREA DRUG | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-06-22 | — | — | EP | disclosed |
| EP-4014978-A1 | COMBINATION PRODUCT CONTAINING LIMONOID AND ?-GLUCOSIDASE INHIBITOR | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-06-22 | — | — | EP | disclosed |
| CN-109381471-B | Combination product comprising limonoids and biguanides | 浙江养生堂天然药物研究所有限公司 | 2022-06-03 | — | — | CN | disclosed |
| US-20220125757-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND BIGUANIDE COMPOUND | ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) | 2022-04-28 | — | — | US | disclosed |
| US-11253567-B2 | Citrus seed extract-containing composition, food, drug, and method for producing citrus seed extract-containing composition | KIKKOMAN CORPORATION (JP) | 2022-02-22 | — | — | US | disclosed |
| US-11253567-B2 | Citrus seed extract-containing composition, food, drug, and method for producing citrus seed extract-containing composition | KIKKOMAN CORPORATION (JP) | 2022-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220296566-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND ALPHA-GLUCOSIDASE INHIBITOR | GANAB, GAA, GANC | CYP3A4 723/4885USP2 4616/4885SLCO1B3 304/4885 |
| US-20220125757-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND BIGUANIDE COMPOUND | LIMK1, LIMK2, SLC5A2 | CYP3A4 1265/4885USP2 4670/4885SLCO1B3 362/4885 |
| US-20220313708-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND SGLT-2 INHIBITOR | SLC5A2, SLC5A1, LCT | CYP3A4 679/4885USP2 4644/4885SLCO1B3 21/4885 |
| US-20220296615-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND SULFONYLUREA COMPOUND | IAPP, GLP1R, SLC5A2 | CYP3A4 536/4885USP2 4513/4885SLCO1B3 184/4885 |
| US-11679097-B2 | Combination product containing limonoid compound and biguanide compound | LIMK1, LIMK2, SLC5A2 | CYP3A4 1265/4885USP2 4670/4885SLCO1B3 362/4885 |
| US-20220226283-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND DPP-4 INHIBITOR | DPP4, DPP3, DPP9 | CYP3A4 117/4885USP2 3913/4885SLCO1B3 333/4885 |
| US-11253567-B2 | Citrus seed extract-containing composition, food, drug, and method for producing citrus seed extract-containing composition | OCIAD1, MLN, OCIAD2 | CYP3A4 330/4885USP2 3643/4885SLCO1B3 1798/4885 |
| US-20250213601-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES | ACE2, FURIN, SARS1 | CYP3A4 64/4885USP2 908/4885SLCO1B3 477/4885 |
| US-20220288046-A1 | COMBINATION PRODUCT CONTAINING LIMONOID COMPOUND AND THIAZOLIDINEDIONE COMPOUND | PPARD, PPARA, PPARG | CYP3A4 179/4885USP2 4858/4885SLCO1B3 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.