Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394047 | 1.00 | FFAR1 (0.46) | FFAR1FFAR4PKMPIK3CDABL1 | |
| SCHEMBL29440624 | 0.85 | PKM (0.56) | PKMMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL972013 | 0.85 | PKM (0.56) | PKMMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL31314166 | 0.82 | FFAR1 (0.43) | FFAR1FFAR4PKMSCDSCD5 | |
| SCHEMBL1808652 | 0.81 | FFAR1 (0.48) | FFAR1FFAR4PKMMAPTMEN1 | |
| SCHEMBL546111 | 0.81 | TDP1 (0.38) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL30294538 | 0.81 | FFAR1 (0.48) | FFAR1FFAR4PKMMAPTMEN1 | |
| SCHEMBL4749281 | 0.79 | FFAR1 (0.47) | FFAR1FFAR4SLC6A4GAA | |
| SCHEMBL30755347 | 0.79 | FFAR1 (0.47) | FFAR1FFAR4SLC6A4GAA | |
| Fluoride SCHEMBL28350549 | 0.79 | FFAR1 (0.47) | FFAR1FFAR4PKMMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038462-A2 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| CN-114072398-B | Compounds that inhibit TDG activity | 上海仕谱生物科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-114072398-A | Compounds that inhibit TDG activity | 上海仕谱生物科技有限公司 | 2022-02-18 | — | — | CN | disclosed |