Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1808652 | 0.98 | FFAR1 (0.48) | FFAR1FFAR4L3MBTL1TDP1CYP1A2 | |
| SCHEMBL30294538 | 0.98 | FFAR1 (0.48) | FFAR1FFAR4L3MBTL1TDP1CYP1A2 | |
| SCHEMBL31314166 | 0.84 | FFAR1 (0.43) | FFAR1FFAR4L3MBTL1TDP1CYP1A2 | |
| SCHEMBL2859876 | 0.83 | FFAR1 (0.46) | FFAR1FFAR4L3MBTL1TDP1CYP1A2 | |
| SCHEMBL4355667 | 0.82 | PKM (0.59) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12668117 | 0.82 | FFAR1 (0.43) | FFAR1FFAR4L3MBTL1TDP1CYP1A2 | |
| SCHEMBL8297680 | 0.81 | CYP1A2 (0.44) | FFAR1FFAR4L3MBTL1TDP1CYP1A2 | |
| SCHEMBL12435311 | 0.80 | FFAR1 (0.41) | FFAR1FFAR4L3MBTL1TDP1CYP1A2 | |
| SCHEMBL2523519 | 0.79 | L3MBTL1 (0.53) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL394047 | 0.79 | FFAR1 (0.46) | FFAR1FFAR4L3MBTL1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612296-A | Phenyl derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-24 | — | — | CN | disclosed |