SCHEMBL29386

SCHEMBL29386

COc1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.58
HTT P42858 5/20 0.58
HPGD P15428 4/20 0.58
KDM4E B2RXH2 3/20 0.58
ALDH1A1 P00352 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
HSD17B10 Q99714 2/20 0.58
LMNA P02545 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.51
ATM Q13315 2/20 0.50
EDNRA P25101 1/20 0.46
METAP2 P50579 1/20 0.44
PKM P14618 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
HTR6 P50406 1/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17691641 0.94 KDM4E (0.53) MAPTHTTHPGDKDM4EALDH1A1
SCHEMBL28988538 0.93 MAPT (0.68) MAPTHTTHPGDKDM4EALDH1A1
SCHEMBL30352484 0.93 MAPT (0.68) MAPTHTTHPGDKDM4EALDH1A1
SCHEMBL16171511 0.91 MAPT (0.50) MAPTHTTHPGDKDM4EALDH1A1
SCHEMBL29539968 0.91 MAPT (0.62) MAPTHTTHPGDKDM4EALDH1A1
SCHEMBL29415 0.91 MAPT (0.62) MAPTHTTHPGDKDM4EALDH1A1
SCHEMBL15435752 0.90 MAPT (0.55) MAPTHTTHPGDKDM4EALDH1A1
SCHEMBL12628264 0.90 MAPT (0.55) MAPTHTTHPGDKDM4EALDH1A1
SCHEMBL12628267 0.90 MAPT (0.55) MAPTHTTHPGDKDM4EALDH1A1
SCHEMBL15074751 0.90 MAPT (0.54) MAPTHTTHPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022257817-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS 清华大学 2022-12-15 WO disclosed
US-10644243-B2 N-phenyl triscarbazole NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-05-05 US disclosed
US-20190259964-A1 ORGANIC SEMICONDUCTOR COMPOSITION AND SEMICONDUCTING LAYER OBTAINED THEREFROM SOLVAY SA (BE) 2019-08-22 US disclosed
WO-2017216168-A1 ORGANIC SEMICONDUCTOR COMPOSITION AND SEMICONDUCTING LAYER OBTAINED THEREFROM SOLVAY SA (BE) 2017-12-21 WO disclosed
EP-3257849-A1 ORGANIC SEMICONDUCTOR COMPOSITION AND SEMICONDUCTING LAYER OBTAINED THEREFROM Solvay SA (BE) 2017-12-20 EP disclosed
EP-2609080-B1 N-PHENYL TRISCARBAZOLE SOLVAY (BE) 2016-03-30 EP disclosed
EP-2609080-B1 N-PHENYL TRISCARBAZOLE SOLVAY (BE) 2016-03-30 EP disclosed
EP-2609080-A1 N-PHENYL TRISCARBAZOLE Solvay SA (BE) 2013-07-03 EP disclosed
EP-2433928-A1 N-phenyl triscarbazole Solvay SA (BE) 2012-03-28 EP disclosed
EP-2433928-A1 N-phenyl triscarbazole Solvay SA (BE) 2012-03-28 EP disclosed
WO-2012025510-A1 N-PHENYL TRISCARBAZOLE SOLVAY SA (BE) 2012-03-01 WO disclosed
WO-2012025510-A1 N-PHENYL TRISCARBAZOLE SOLVAY SA (BE) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10644243-B2 N-phenyl triscarbazole RB1, LBR, NR1I2 MAPT 3361/4885HTT 933/4885HPGD 1980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.