SCHEMBL15435752

SCHEMBL15435752

COc1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccc(-n5c6ccccc6c6ccccc65)cc4)ccc32)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.55
ALDH1A1 P00352 4/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
KDM4E B2RXH2 3/20 0.55
HPGD P15428 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
HTT P42858 2/20 0.55
HSD17B10 Q99714 1/20 0.55
TSPO P30536 3/20 0.52
LMNA P02545 1/20 0.51
EDNRA P25101 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
ATM Q13315 2/20 0.47
KDR P35968 1/20 0.45
OXTR P30559 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
GRIK2 Q13002 1/20 0.43
GLA P06280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12628264 1.00 MAPT (0.55) MAPTALDH1A1L3MBTL1KDM4EHPGD
SCHEMBL12628267 1.00 MAPT (0.55) MAPTALDH1A1L3MBTL1KDM4EHPGD
SCHEMBL13086803 0.97 MAPT (0.53) MAPTALDH1A1L3MBTL1KDM4EHPGD
SCHEMBL16171615 0.96 MAPT (0.51) MAPTALDH1A1L3MBTL1KDM4EHPGD
SCHEMBL15435800 0.94 MAPT (0.50) MAPTALDH1A1L3MBTL1KDM4EHPGD
SCHEMBL16171511 0.94 MAPT (0.50) MAPTALDH1A1L3MBTL1KDM4EHPGD
SCHEMBL16171589 0.93 KDM4E (0.59) MAPTALDH1A1L3MBTL1KDM4EHPGD
SCHEMBL16171512 0.92 MAPT (0.48) MAPTALDH1A1L3MBTL1KDM4EHPGD
SCHEMBL17998131 0.92 MAPT (0.48) MAPTALDH1A1L3MBTL1KDM4EHPGD
SCHEMBL12056697 0.92 TSPO (0.49) MAPTALDH1A1L3MBTL1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 US disclosed
EP-2688120-B1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT TORAY INDUSTRIES (JP) 2017-08-23 EP disclosed
US-9564595-B2 Bis-carbazole derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-02-07 US disclosed
US-9564595-B2 Bis-carbazole derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-02-07 US disclosed
US-9537107-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2017-01-03 US disclosed
US-20140306207-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-16 US disclosed
EP-2688120-A1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT Toray Industries, Inc. (JP) 2014-01-22 EP disclosed
US-20140008633-A1 BIS-CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MITSUI CHEMICALS, INC (JP) 2014-01-09 US disclosed
US-20140008633-A1 BIS-CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MITSUI CHEMICALS, INC (JP) 2014-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 MAPT 716/4885ALDH1A1 816/4885L3MBTL1 1678/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 MAPT 716/4885ALDH1A1 816/4885L3MBTL1 1678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.