⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620931 | 1.00 | — | — | |
| SCHEMBL980780 | 0.85 | LMNA (0.31) | — | |
| SCHEMBL10751233 | 0.82 | — | — | |
| SCHEMBL10477524 | 0.82 | TSHR (0.32) | — | |
| SCHEMBL30839620 | 0.78 | PDE4A (0.44) | — | |
| SCHEMBL28987639 | 0.78 | PDE4A (0.44) | — | |
| SCHEMBL30839622 | 0.78 | PDE4A (0.44) | — | |
| SCHEMBL5503862 | 0.77 | — | — | |
| SCHEMBL11849643 | 0.76 | TSHR (0.35) | — | |
| SCHEMBL9108031 | 0.73 | LMNA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023038519-A1 | MODIFICATION OF BIOPOLYMERS USING POLYOLS AND POLYACIDS | TECHNISCHE UNIVERSITEIT DELFT (NL) | 2023-03-16 | — | — | WO | disclosed |
| CN-114040779-A | Conjugates of cell binding molecules containing branched linkers and cytotoxic agents | 杭州多禧生物科技有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-114040781-A | Formulation of conjugate of TUBULYSIN derivative and cell binding molecule | 杭州多禧生物科技有限公司 | 2022-02-11 | — | — | CN | disclosed |