SCHEMBL980780

SCHEMBL980780

O=C(C(O)C(O)C(O)C(O)C(O)C(O)C(O)C(=O)S(=O)(=O)O)S(=O)(=O)O

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10477524 0.91 TSHR (0.32) MEN1ALDH1A1TSHRKMT2A
SCHEMBL30839620 0.87 PDE4A (0.44) LMNAALDH1A1TSHR
SCHEMBL28987639 0.87 PDE4A (0.44) LMNAALDH1A1TSHR
SCHEMBL30839622 0.87 PDE4A (0.44) LMNAALDH1A1TSHR
SCHEMBL29386396 0.85
SCHEMBL11849643 0.84 TSHR (0.35) MEN1ALDH1A1TSHRKMT2A
SCHEMBL979873 0.81 LMNA (0.57) LMNA
SCHEMBL9108031 0.81 LMNA (0.57) LMNA
SCHEMBL31544298 0.79 LMNA (0.55) LMNA
SCHEMBL30469495 0.78 LMNA (0.48) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10164196-B2 Aniline derivative, charge-transporting varnish and organic electroluminescent device NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-12-25 US disclosed
EP-3012245-B1 ANILINE DERIVATIVE, CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT DEVICE NISSAN CHEMICAL IND LTD (JP) 2018-08-08 EP disclosed
US-20160141507-A1 ANILINE DERIVATIVE, CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT DEVICE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-19 US disclosed
EP-3012245-A1 ANILINE DERIVATIVE, CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT DEVICE Nissan Chemical Industries, Ltd. (JP) 2016-04-27 EP disclosed
US-7868050-B2 Sulfonated aryl sulfonate matrices and method of production SCHINDLER BERND 2011-01-11 US disclosed
US-7160927-B2 Sulfonated aryl sulfonate matrices and method of production SCHINDLER BERND 2007-01-09 US disclosed
US-20060276602-A1 Sulfonated aryl sulfonate matrices and method of production SCHINDLER BERND 2006-12-07 US disclosed
US-20040054125-A1 Sulfonated aryl sulfonate matrices and method of production SCHINDLER BERND (DE) 2004-03-18 US disclosed
EP-1278589-A2 SULFONATED ARYL SULFONATE MATRICES AND METHOD OF PRODUCTION Schindler, Bernd (DE) 2003-01-29 EP disclosed
WO-2001083091-A2 SULFONATED ARYL SULFONATE MATRICES AND METHOD OF PRODUCTION SCHINDLER BERND (DE) 2001-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10164196-B2 Aniline derivative, charge-transporting varnish and organic electroluminescent device SLC7A5, SLC43A1, SLC9A5 LMNA 3558/4885MEN1 4343/4885ALDH1A1 116/4885
US-20160141507-A1 ANILINE DERIVATIVE, CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT DEVICE SLC7A5, SLC43A1, SLC9A5 LMNA 3558/4885MEN1 4343/4885ALDH1A1 116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.