Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.51 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12354143 | 1.00 | GPR119 (0.55) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL28834093 | 0.93 | USP30 (0.60) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL30958653 | 0.93 | USP30 (0.60) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL28834091 | 0.93 | USP30 (0.60) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL1787609 | 0.89 | GPR119 (0.61) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL22050474 | 0.88 | NAMPT (0.64) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL22051946 | 0.88 | NAMPT (0.64) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL4457404 | 0.88 | NAMPT (0.48) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL3843148 | 0.88 | NAMPT (0.66) | GPR119NAMPTPTPN2PTPN1PTPN6 | |
| SCHEMBL22945386 | 0.87 | USP30 (0.64) | USP30HPGDSNR1H2RXRANR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114533729-A | Glucosylceramide synthase inhibitors | 建新公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108864076-B | Glucosylceramide synthase inhibitors | 建新公司 | 2022-02-11 | — | — | CN | disclosed |