Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.64 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.59 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.57 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22051946 | 1.00 | NAMPT (0.64) | NAMPTGPR119USP30PTPN2PTPN1 | |
| SCHEMBL3843148 | 0.92 | NAMPT (0.66) | NAMPTGPR119PTPN2PTPN1PTPN6 | |
| Acetic Acid SCHEMBL29880486 | 0.89 | NAMPT (0.63) | NAMPTGPR119HPGDSKDM4EPKM | |
| SCHEMBL12354143 | 0.88 | GPR119 (0.55) | NAMPTGPR119USP30PTPN2PTPN1 | |
| SCHEMBL29386809 | 0.88 | GPR119 (0.55) | NAMPTGPR119USP30PTPN2PTPN1 | |
| Dimethylamine SCHEMBL6608623 | 0.88 | NAMPT (0.65) | NAMPTGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL31616130 | 0.87 | NAMPT (0.61) | NAMPTGPR119USP30HPGDSKDM4E | |
| SCHEMBL22944633 | 0.86 | USP30 (0.59) | NAMPTGPR119USP30PTPN2PTPN1 | |
| Trifluoroacetic Acid SCHEMBL29880449 | 0.85 | NAMPT (0.60) | NAMPTGPR119P2RY14HPGDSKDM4E | |
| SCHEMBL226854 | 0.85 | NAMPT (0.59) | NAMPTGPR119PTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017486-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2022-01-20 | — | — | US | disclosed |
| EP-3888651-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | Kyushu University, National University Corporation (JP) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017486-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | DOCK2, DOCK11, DOCK5 | NAMPT 3258/4885GPR119 1422/4885USP30 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.