Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.59 |
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | NPC1 | O15118 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | GFER | P55789 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | GLA | P06280 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.57 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16273449 | 1.00 | NT5E (0.78) | NT5ESMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL21887627 | 0.94 | NT5E (0.89) | NT5ESMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL14684214 | 0.88 | NT5E (0.61) | NT5ESMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL23119357 | 0.88 | NT5E (1.00) | NT5ESMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL9862039 | 0.85 | ALDH1A1 (0.69) | NT5ESMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL30307784 | 0.85 | ALDH1A1 (0.74) | NT5ESMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL159873 | 0.85 | ALDH1A1 (0.74) | NT5ESMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL28312335 | 0.85 | ALDH1A1 (0.74) | NT5ESMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL13400661 | 0.84 | NT5E (0.56) | NT5EGAASLC2A1NPBWR1RPS6KA3 | |
| SCHEMBL1655753 | 0.83 | MEN1 (0.73) | NT5ESMN1; SMN2MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11246857-B2 | Anti-fungal inhibitors | UNIV JOHNS HOPKINS (US) | 2022-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11246857-B2 | Anti-fungal inhibitors | ERG28, DPM1, HIF1AN | NT5E 1104/4885SMN1; SMN2 4735/4885MAPT 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.