Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 14/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.55 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2941948 | 0.90 | MLYCD (0.57) | MLYCDHSD11B1NR1H3NR1H2 | |
| SCHEMBL2940871 | 0.86 | MLYCD (0.59) | MLYCDHSD11B1 | |
| SCHEMBL6839027 | 0.84 | MLYCD (0.61) | MLYCDHSD11B1 | |
| SCHEMBL2938750 | 0.81 | MLYCD (0.60) | MLYCDNR1H3NR1H2 | |
| SCHEMBL6843906 | 0.80 | MLYCD (0.61) | MLYCDNR1H3NR1H2 | |
| SCHEMBL6843778 | 0.77 | MLYCD (0.64) | MLYCDNR1H3NR1H2 | |
| SCHEMBL6843613 | 0.74 | MLYCD (0.71) | MLYCDNR1H3NR1H2 | |
| SCHEMBL2942135 | 0.73 | MLYCD (0.69) | MLYCDNR1H3NR1H2 | |
| SCHEMBL4988361 | 0.71 | MLYCD (1.00) | MLYCD | |
| SCHEMBL13431598 | 0.71 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4503232-B2 | — | — | 2010-07-14 | — | — | JP | claimed |
| JP-2004521113-A | — | — | 2004-07-15 | — | — | JP | claimed |
| EP-1353662-A2 | METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-10-22 | — | — | EP | claimed |
| WO-2002058690-A2 | METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-08-01 | — | — | WO | claimed |