SCHEMBL29387355

SCHEMBL29387355

CCC(C)C1NC(=O)C(N)CSSCC(C(=O)N2CCCC2C(=O)NC(CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCCN=C(N)N)NC(=O)C(C(C)CC)NC1=O

nearest known ligand 0.73

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ AVPR1A P37288 9/20 0.73
▸ AVPR1B P47901 9/20 0.73
▸ OXTR P30559 7/20 0.72
▸ AVPR2 P30518 6/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15511399 0.92 AVPR1A (0.78) AVPR1AAVPR1BOXTRAVPR2
Vasotocin SCHEMBL15511347 0.91 OXTR (0.86) AVPR1AAVPR1BOXTRAVPR2
Vasotocin SCHEMBL15511393 0.91 OXTR (0.86) AVPR1AAVPR1BOXTRAVPR2
Vasotocin SCHEMBL13331 0.91 OXTR (0.86) AVPR1AAVPR1BOXTRAVPR2
Argiprestocin SCHEMBL30424966 0.91 OXTR (0.86) AVPR1AAVPR1BOXTRAVPR2
SCHEMBL15511428 0.88 OXTR (0.82) AVPR1AAVPR1BOXTRAVPR2
SCHEMBL29618038 0.85 OXTR (0.86) AVPR1AAVPR1BOXTRAVPR2
Selepressin SCHEMBL19712231 0.85 OXTR (0.82) AVPR1AAVPR1BOXTRAVPR2
Selepressin SCHEMBL28487360 0.85 OXTR (0.82) AVPR1AAVPR1BOXTRAVPR2
Selepressin SCHEMBL19712230 0.85 OXTR (0.82) AVPR1AAVPR1BOXTRAVPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4140485-A1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV Gilead Sciences, Inc. (US) 2023-03-01 — — EP claimed
EP-3423091-B1 COMPOSITIONS AND METHODS FOR INDUCING HIV-1 ANTIBODIES UNIV DUKE (US) 2026-05-06 — — EP disclosed
US-12305211-B2 Protein glycosylation sites by rapid expression and characterization of N-glycosyltransferases NORTHWESTERN UNIVERSITY (US) 2025-05-20 — — US disclosed
US-20250144050-A1 AMINOTHIOL-CONJUGATES, COMPOSITIONS, AND METHODS OF USE THEREOF THE BURLINGTON HC RESEARCH GROUP, INC. 2025-05-08 — — US disclosed
WO-2025078698-A1 FUSION PROTEINS FOR THE TREATMENT OF VIRAL INFECTIONS FUNDACIÓN INVESTIGACIÓN BIOMÉDICA HOSPITAL UNIVERSITARIO 12 DE OCTUBRE (ES) 2025-04-17 — — WO disclosed
US-20250073328-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HIV INFECTION US GOV VETERANS AFFAIRS (US) 2025-03-06 — — US disclosed
CN-119523989-A Compounds and compositions for treating microwave radiation induced brain injury by modulating GABA-alpha 5 中国人民解放军军事科学院军事医学研究院 2025-02-28 — — CN disclosed
US-20240390482-A1 HIV-1 ENVELOPE GLYCOPEPTIDE NANOPARTICLES AND THEIR USES UNIV DUKE (US) 2024-11-28 — — US disclosed
US-20240376510-A1 DESIGN OF PROTEIN GLYCOSYLATION SITES BY RAPID EXPRESSION AND CHARACTERIZATION OF N-GLYCOSYLTRANSFERASES NORTHWESTERN UNIVERSITY 2024-11-14 — — US disclosed
CN-118859787-A Method for learning and calibrating automobile seat position 昌辉汽车电气系统(安徽)有限公司 2024-10-29 — — CN disclosed
US-20230140293-A1 COMPOSITIONS COMPRISING MODIFIED HIV ENVELOPES DUKE UNIVERSITY 2023-05-04 — — US disclosed
CN-218829874-U Frequency hopping filter 上海鸿晔电子科技股份有限公司 2023-04-07 — — CN disclosed
WO-2023028316-A1 AMINOTHIOL-CONJUGATES, COMPOSITIONS, AND METHODS OF USE THEREOF THE BURLINGTON HC RESEARCH GROUP, INC. (US) 2023-03-02 — — WO disclosed
EP-4140485-A1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV Gilead Sciences, Inc. (US) 2023-03-01 — — EP disclosed
WO-2022192262-A1 HIV-1 ENVELOPE GLYCOPEPTIDE NANOPARTICLES AND THEIR USES DUKE UNIVERSITY (US) 2022-09-15 — — WO disclosed
EP-3166607-B1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV GILEAD SCIENCES INC (US) 2022-08-31 — — EP disclosed
US-20220235389-A1 Design of Protein Glycosylation Sites by Rapid Expression and Characterization of N-Glycosyltransferases NORTHWESTERN UNIVERSITY (US) 2022-07-28 — — US disclosed
US-11318197-B2 Compositions and methods for inducing HIV-1 antibodies DUKE UNIVERSITY (US) 2022-05-03 — — US disclosed
US-20220062293-A1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV GILEAD SCIENCES, INC. 2022-03-03 — — US disclosed
US-20220041650-A1 PURIFICATION METHOD FOR RECOMBINANT PROTEINS AND NANOPARTICLES UNIV DUKE (US) 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250073328-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HIV INFECTION CD4, C9, C1S AVPR1A 1122/4885AVPR1B 1576/4885OXTR 3881/4885
US-20250144050-A1 AMINOTHIOL-CONJUGATES, COMPOSITIONS, AND METHODS OF USE THEREOF TIAL1, SLC7A11, MGMT AVPR1A 4472/4885AVPR1B 4578/4885OXTR 2542/4885
US-20220062293-A1 MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV TLR7, TLR3, TLR6 AVPR1A 1196/4885AVPR1B 926/4885OXTR 1283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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