Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 7/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 10/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251869 | 0.80 | FGFR4 (0.62) | FGFR4FGFR1TNK2FGFR2FGFR3 | |
| SCHEMBL28911435 | 0.80 | FGFR4 (0.62) | FGFR4FGFR1TNK2FGFR2FGFR3 | |
| SCHEMBL4316054 | 0.77 | TNK2 (0.48) | FGFR1TNK2FGFR2IGF1R | |
| SCHEMBL398874 | 0.77 | FGFR2 (0.57) | FGFR1TNK2FGFR2IGF1R | |
| SCHEMBL28911444 | 0.76 | FGFR4 (0.49) | FGFR4FGFR1TNK2FGFR2FGFR3 | |
| SCHEMBL28911445 | 0.76 | FGFR4 (0.49) | FGFR4FGFR1TNK2FGFR2FGFR3 | |
| SCHEMBL2574101 | 0.74 | TNK2 (0.48) | FGFR4FGFR1TNK2FGFR2FGFR3 | |
| SCHEMBL1129345 | 0.73 | TNK2 (0.56) | FGFR1TNK2FGFR2IGF1R | |
| SCHEMBL402054 | 0.73 | TNK2 (0.59) | TNK2FGFR2IGF1R | |
| SCHEMBL401909 | 0.73 | TNK2 (0.59) | TNK2FGFR2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033532-A1 | FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |