Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 8/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ABL1 | P00519 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.53 |
| ▸ | TUBB | P07437 | 6/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26075190 | 0.91 | KDR (0.58) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL26075187 | 0.91 | KDR (0.58) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL3500745 | 0.89 | LMNA (0.64) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL14643045 | 0.89 | LMNA (0.64) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL30446693 | 0.82 | LMNA (0.55) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL29569607 | 0.81 | KDR (0.71) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| Flubendazole SCHEMBL6232065 | 0.81 | KDR (1.00) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| Flubendazole SCHEMBL31704404 | 0.81 | KDR (1.00) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL3500740 | 0.80 | LMNA (0.55) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL14375407 | 0.79 | TEK (0.76) | KDRTEKRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230301968-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLUBENDAZOLE | ZEPHAPHARM LTD (GB) | 2023-09-28 | — | — | US | disclosed |
| EP-3972591-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLUBENDAZOLE | ZEPHAPHARM LTD (GB) | 2022-12-28 | — | — | EP | disclosed |
| EP-3972591-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLUBENDAZOLE | Zephapharm Ltd. (GB) | 2022-03-30 | — | — | EP | disclosed |
| WO-2022034275-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLUBENDAZOLE | ZEPHAPHARM LTD (GB) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230301968-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLUBENDAZOLE | CYP3A43, CYP1A2, CYP3A5 | KDR 4262/4885MAPK1 2619/4885ADORA3 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.