Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | ABL1 | P00519 | 2/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.80 |
| ▸ | HTT | P42858 | 2/20 | 0.80 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.80 |
| ▸ | USP2 | O75604 | 1/20 | 0.80 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.65 |
| ▸ | TUBB | P07437 | 3/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flubendazole SCHEMBL31704404 | 1.00 | KDR (1.00) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| Flubendazole SCHEMBL28086273 | 0.91 | KDR (0.82) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| Flubendazole SCHEMBL167185 | 0.90 | KDR (0.82) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| Flubendazole SCHEMBL29409278 | 0.90 | KDR (0.82) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| Flubendazole SCHEMBL22321861 | 0.89 | KDR (0.80) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| Mebendazole SCHEMBL536464 | 0.89 | ABL1 (1.00) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| Mebendazole SCHEMBL29390263 | 0.89 | ABL1 (1.00) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL24209473 | 0.89 | KDR (0.79) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| Flubendazole SCHEMBL28142848 | 0.88 | LMNA (0.77) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL14375449 | 0.88 | KDR (0.80) | KDRMAPK1ADORA3PTGS1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3972591-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLUBENDAZOLE | ZEPHAPHARM LTD (GB) | 2022-12-28 | — | — | EP | claimed |
| CN-115697058-B | Agrochemical adjuvants | 禾大国际股份公开有限公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4389116-A1 | PHARMACEUTICAL AQUEOUS FLUBENDAZOLE SUSPENSION | Dechra Ltd (GB) | 2024-06-26 | — | — | EP | disclosed |
| CN-117825570-A | Method for simultaneously detecting imidazole drugs and metabolic residues thereof in food | 重庆市计量质量检测研究院 | 2024-04-05 | — | — | CN | disclosed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-117616018-A | Herbicidal aryl dihydrofuran carboxylic acid esters | 巴斯夫欧洲公司 | 2024-02-27 | — | — | CN | disclosed |
| US-20240050444-A1 | TREATMENT METHODS | VASCULAR THERAPEUTICS PTY LTD (AU) | 2024-02-15 | — | — | US | disclosed |
| US-20240050943-A1 | MULTI-VOLUME MICROCHAMBER-BASED MICROFLUIDIC PLATFORM AND USE THEREOF | CORNELL UNIVERSITY | 2024-02-15 | — | — | US | disclosed |
| US-20240050950-A1 | GRADIENT-BASED MICROFLUIDIC CIRCUIT, DEVICE, AND METHOD FOR PERFORMING AN ASSAY | CORNELL UNIVERSITY | 2024-02-15 | — | — | US | disclosed |
| CN-117561242-A | 4-methylsulfonyl benzamide compound, preparation method, weeding composition and application | 江苏中旗科技股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-2846788-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF PAIN | Akron Molecules AG (AT) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013167743-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF PAIN | AKRON MOLECULES GMBH (AT) | 2013-11-14 | — | — | WO | disclosed |
| US-20130137099-A1 | TRANSGENIC REPORTER SYSTEM THAT REVEALS EXPRESSION PROFILES AND REGULATION MECHANISMS OF ALTERNATIVE SPLICING IN MAMMALIAN ORGANISMS | KYOTO UNIVERSITY (JP) | 2013-05-30 | — | — | US | disclosed |
| US-20120202840-A1 | Use of Flubendazole and Vinca Alkaloids for Treatment of Hematological Diseases | UNIVERSITY HEALTH NETWORK (CA) | 2012-08-09 | — | — | US | disclosed |
| US-20120202840-A1 | Use of Flubendazole and Vinca Alkaloids for Treatment of Hematological Diseases | UNIVERSITY HEALTH NETWORK (CA) | 2012-08-09 | — | — | US | disclosed |
| WO-2011041914-A1 | USE OF FLUBENDAZOLE AND VINCA ALKALOIDS FOR TREATMENT OF HEMATOLOGICAL DISEASES | UNIVERSITY HEALTH NETWORK (UHN) (CA) | 2011-04-14 | — | — | WO | disclosed |
| EP-0896517-B1 | METHOD FOR PROMOTING HAIR, NAIL, AND SKIN KERATINIZATION | SCHICK MARY P (US) | 2005-05-25 | — | — | EP | disclosed |
| US-5861142-A | DERMATOLOGY AND GROWTH OF HAIR NAILS AND SKIN | SCHICK MARY PICHLER (US) | 1999-01-19 | — | — | US | disclosed |
| EP-0090368-B1 | ANTHELMINTIC PREPARATIONS | HOECHST UK LIMITED (GB) | 1987-09-02 | — | — | EP | disclosed |
| EP-0224249-A1 | Amorphous benzimidazole derivatives | SYNTEX (U.S.A.) INC. (US) | 1987-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240050444-A1 | TREATMENT METHODS | FOSB, FOS, VCAM1 | KDR 6/4885MAPK1 91/4885ADORA3 4166/4885 |
| US-20120202840-A1 | Use of Flubendazole and Vinca Alkaloids for Treatment of Hematological Diseases | MCL1, BCL9, KIT | KDR 2342/4885MAPK1 3216/4885ADORA3 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.