Sugi Predict

Sugi Predict / Compounds / SCHEMBL29389060

SCHEMBL29389060

SCHEMBL29389060

CC[C@H](C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)CN)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O

nearest known ligand 0.72

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CALCR P30988 5/20 0.72
▸ APLNR P35414 2/20 0.62
▸ CRHR1 P34998 1/20 0.61
▸ CRHR2 Q13324 1/20 0.61
▸ HCRTR1 O43613 1/20 0.59
▸ HCRTR2 O43614 1/20 0.59
▸ GLP1R P43220 4/20 0.59
▸ NPY2R P49146 4/20 0.58
▸ NPY4R P50391 4/20 0.58
▸ NPY5R Q15761 4/20 0.58
▸ NPY1R P25929 3/20 0.58
▸ GCGR P47871 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29652674 0.93 CALCR (0.73) CALCRAPLNRCRHR1CRHR2HCRTR1
SCHEMBL30884870 0.92 CALCR (0.75) CALCRCRHR1CRHR2GLP1RNPY2R
SCHEMBL30658357 0.91 CALCR (0.75) CALCRAPLNRCRHR1CRHR2HCRTR1
SCHEMBL31419713 0.91 CALCR (0.73) CALCRCRHR1CRHR2GLP1RNPY2R
SCHEMBL30658226 0.90 CALCR (0.77) CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL31148882 0.90 CALCR (0.78) CALCRCRHR1CRHR2HCRTR1HCRTR2
SCHEMBL29494575 0.89 CALCR (0.76) CALCRHCRTR1HCRTR2GLP1RNPY2R
SCHEMBL30686820 0.89 CALCR (0.76) CALCRHCRTR1HCRTR2GLP1RNPY2R
SCHEMBL30686827 0.89 CALCR (0.76) CALCRHCRTR1HCRTR2GLP1RNPY2R
SCHEMBL30658284 0.89 CALCR (0.76) CALCRCRHR1CRHR2HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240389602-A1 LIPOSOME FORMULATIONS FOR PESTICIDE DELIVERY AND METHODS FOR PRODUCING AND USING THE SAME SUTERRA LLC 2024-11-28 — — US disclosed
US-20240366627-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2024-11-07 — — US disclosed
US-11963964-B2 Small molecules for mouse satellite cell proliferation PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-04-23 — — US disclosed
US-20240041038-A1 INSECTICIDAL COMBINATIONS Vestaron Corporation (US) 2024-02-08 — — US disclosed
EP-4312536-A1 LIPOSOME FORMULATIONS FOR PESTICIDE DELIVERY AND METHODS FOR PRODUCING AND USING THE SAME Vestaron Corporation (US) 2024-02-07 — — EP disclosed
CN-116096236-A Insecticidal combinations 韦斯塔隆公司 2023-05-09 — — CN disclosed
EP-4142498-A1 INSECTICIDAL COMBINATIONS Vestaron Corporation (US) 2023-03-08 — — EP disclosed
WO-2022212863-A1 LIPOSOME FORMULATIONS FOR PESTICIDE DELIVERY AND METHODS FOR PRODUCING AND USING THE SAME Vestaron Corporation (US) 2022-10-06 — — WO disclosed
US-11426400-B2 Methods of increasing satellite cell proliferation with vorinostat or bosutinib PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-08-30 — — US disclosed
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2022-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 CALCR 3059/4885APLNR 516/4885CRHR1 4675/4885
US-20240366627-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 CALCR 3059/4885APLNR 516/4885CRHR1 4675/4885
US-11963964-B2 Small molecules for mouse satellite cell proliferation MKI67, MYLK2, MYH2 CALCR 3059/4885APLNR 516/4885CRHR1 4675/4885
US-11426400-B2 Methods of increasing satellite cell proliferation with vorinostat or bosutinib MKI67, CDK4, CDKN1A CALCR 3992/4885APLNR 1754/4885CRHR1 4059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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