SCHEMBL29494575

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)O)C(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C(C)C

nearest known ligand 0.76

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	4/20	0.76

▸	HCRTR1	O43613	1/20	0.69

▸	HCRTR2	O43614	1/20	0.69

▸	NPY2R	P49146	8/20	0.67

▸	NPY4R	P50391	8/20	0.67

▸	NPY5R	Q15761	8/20	0.67

▸	NPY1R	P25929	6/20	0.67

▸	F2	P00734	3/20	0.66

▸	CCKBR	P32239	2/20	0.65

▸	GLP1R	P43220	2/20	0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30686820	1.00	CALCR (0.76)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30686827	1.00	CALCR (0.76)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30686816	0.96	CALCR (0.75)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30686815	0.96	CALCR (0.75)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30686824	0.96	CALCR (0.75)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30686818	0.96	CALCR (0.75)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30686823	0.96	CALCR (0.75)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30686832	0.96	CALCR (0.75)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30686821	0.96	CALCR (0.75)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30686817	0.96	CALCR (0.75)	CALCRHCRTR1HCRTR2NPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110945017-B	Bifunctional compounds	诺和诺德股份有限公司	2024-07-16	—	—	CN	disclosed
US-11649269-B2	Bifunctional compounds comprising insulin peptides and EGF(A) peptides	NOVO NORDISK A/S (DK)	2023-05-16	—	—	US	disclosed
US-20230000949-A1	SOLID COMPOSITIONS COMPRISING A PCSK9 INHIBITOR AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID	NOVO NORDISK AS (DK)	2023-01-05	—	—	US	disclosed
US-20220323544-A1	SOLID COMPOSITIONS COMPRISING AN EGF(A) DERIVATIVE AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID	NOVO NORDISK A/S (DK)	2022-10-13	—	—	US	disclosed
EP-3402811-B1	EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS	NOVO NORDISK AS (DK)	2022-03-30	—	—	EP	disclosed
CN-114222581-A	Solid compositions comprising salts of EGF (A) derivatives and N- (8- (2-hydroxybenzoyl) amino) octanoic acid	诺和诺德股份有限公司	2022-03-22	—	—	CN	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-11649269-B2	Bifunctional compounds comprising insulin peptides and EGF(A) peptides	IAPP, IGFBP1, IGFBP2	CALCR 1240/4885HCRTR1 4651/4885HCRTR2 4577/4885
US-20230000949-A1	SOLID COMPOSITIONS COMPRISING A PCSK9 INHIBITOR AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID	PCSK9, EGFR, PCSK6	CALCR 867/4885HCRTR1 3681/4885HCRTR2 3639/4885
US-20220323544-A1	SOLID COMPOSITIONS COMPRISING AN EGF(A) DERIVATIVE AND A SALT OF N-(8-(2-HYDROXYBENZOYL)AMINO)CAPRYLIC ACID	PCSK9, EGFR, PCSK6	CALCR 509/4885HCRTR1 3366/4885HCRTR2 3179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.