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SCHEMBL29389186

SCHEMBL29389186

CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 5/20 0.62
▸ GLP1R P43220 9/20 0.60
▸ KEAP1 Q14145 1/20 0.58
▸ C5AR1 P21730 1/20 0.57
▸ PTH1R Q03431 1/20 0.56
▸ CCKAR P32238 1/20 0.56
▸ CCKBR P32239 1/20 0.56
▸ ECE1 P42892 1/20 0.56
▸ MUS81 Q96NY9 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30037155 1.00 IL23R (0.62) IL23RGLP1RKEAP1C5AR1PTH1R
SCHEMBL29410268 1.00 IL23R (0.62) IL23RGLP1RKEAP1C5AR1PTH1R
SCHEMBL29389409 0.98 IL23R (0.64) IL23RKEAP1PTH1RCCKARCCKBR
SCHEMBL29534029 0.98 IL23R (0.61) IL23RGLP1RKEAP1C5AR1PTH1R
SCHEMBL30037407 0.97 IL23R (0.61) IL23RGLP1RKEAP1C5AR1PTH1R
SCHEMBL29581449 0.94 GLP1R (0.66) IL23RGLP1RECE1MUS81
SCHEMBL29533546 0.93 C5AR1 (0.63) IL23RGLP1RKEAP1C5AR1PTH1R
SCHEMBL29534240 0.93 C5AR1 (0.63) IL23RGLP1RKEAP1C5AR1PTH1R
SCHEMBL29533850 0.93 C5AR1 (0.63) IL23RGLP1RKEAP1C5AR1PTH1R
SCHEMBL29533859 0.93 C5AR1 (0.63) IL23RGLP1RKEAP1C5AR1PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240366627-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2024-11-07 — — US disclosed
US-11963964-B2 Small molecules for mouse satellite cell proliferation PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-04-23 — — US disclosed
US-20220273766-A1 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF MODERNA THERAPEUTICS, INC. 2022-09-01 — — US disclosed
US-11426400-B2 Methods of increasing satellite cell proliferation with vorinostat or bosutinib PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-08-30 — — US disclosed
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2022-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 IL23R 3786/4885GLP1R 2772/4885KEAP1 1345/4885
US-20240366627-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 IL23R 3786/4885GLP1R 2772/4885KEAP1 1345/4885
US-11963964-B2 Small molecules for mouse satellite cell proliferation MKI67, MYLK2, MYH2 IL23R 3786/4885GLP1R 2772/4885KEAP1 1345/4885
US-11426400-B2 Methods of increasing satellite cell proliferation with vorinostat or bosutinib MKI67, CDK4, CDKN1A IL23R 2802/4885GLP1R 2056/4885KEAP1 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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