SCHEMBL29389409

SCHEMBL29389409

CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.64

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 5/20 0.64
▸ CCKBR P32239 9/20 0.59
▸ CCKAR P32238 2/20 0.59
▸ KEAP1 Q14145 1/20 0.59
▸ PTH1R Q03431 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30037155 0.98 IL23R (0.62) IL23RCCKBRCCKARKEAP1PTH1R
SCHEMBL29389186 0.98 IL23R (0.62) IL23RCCKBRCCKARKEAP1PTH1R
SCHEMBL29410268 0.98 IL23R (0.62) IL23RCCKBRCCKARKEAP1PTH1R
SCHEMBL29534029 0.97 IL23R (0.61) IL23RCCKBRCCKARKEAP1PTH1R
SCHEMBL30037407 0.97 IL23R (0.61) IL23RCCKBRCCKARKEAP1PTH1R
SCHEMBL29533546 0.93 C5AR1 (0.63) IL23RCCKBRKEAP1PTH1R
SCHEMBL29533850 0.93 C5AR1 (0.63) IL23RCCKBRKEAP1PTH1R
SCHEMBL29534240 0.93 C5AR1 (0.63) IL23RCCKBRKEAP1PTH1R
SCHEMBL29533859 0.93 C5AR1 (0.63) IL23RCCKBRKEAP1PTH1R
SCHEMBL29533287 0.92 CCKBR (0.60) IL23RCCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11426400-B2 Methods of increasing satellite cell proliferation with vorinostat or bosutinib PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-08-30 — — US disclosed
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2022-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 IL23R 3786/4885CCKBR 1601/4885CCKAR 1370/4885
US-11426400-B2 Methods of increasing satellite cell proliferation with vorinostat or bosutinib MKI67, CDK4, CDKN1A IL23R 2802/4885CCKBR 2397/4885CCKAR 2734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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