Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10109058 | 0.90 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28374088 | 0.86 | ALDH1A1 (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5517050 | 0.82 | HSD17B10 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21547377 | 0.82 | HSD17B10 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12344760 | 0.82 | HSD17B10 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16645332 | 0.82 | HSD17B10 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17971054 | 0.82 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12640341 | 0.82 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL126194 | 0.82 | HSD17B10 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL15468170 | 0.82 | HSD17B10 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105887-A | Aminopyrimidine derivative and preparation method and application thereof | 沈阳药科大学 | 2022-03-01 | — | — | CN | claimed |
| CN-114105887-A | Aminopyrimidine derivative and preparation method and application thereof | 沈阳药科大学 | 2022-03-01 | — | — | CN | disclosed |