Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 5/20 | 0.56 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30186556 | 0.93 | CALCRL (0.55) | CALCRLRAMP1OPRM1OPRD1KEAP1 | |
| SCHEMBL29392795 | 0.91 | CALCRL (0.55) | CALCRLRAMP1OPRM1OPRD1KEAP1 | |
| SCHEMBL29392324 | 0.91 | KEAP1 (0.51) | CALCRLRAMP1OPRM1OPRD1KEAP1 | |
| SCHEMBL29392282 | 0.91 | CALCRL (0.58) | CALCRLRAMP1OPRM1OPRD1 | |
| SCHEMBL29392539 | 0.90 | CALCRL (0.56) | CALCRLRAMP1OPRM1OPRD1KEAP1 | |
| SCHEMBL29392543 | 0.88 | CALCRL (0.54) | CALCRLRAMP1OPRM1OPRD1 | |
| SCHEMBL29392901 | 0.88 | EPHA2 (0.57) | CALCRLRAMP1KEAP1EPHA2 | |
| SCHEMBL30186419 | 0.87 | CALCRL (0.58) | CALCRLRAMP1OPRM1OPRD1KEAP1 | |
| SCHEMBL30186430 | 0.87 | CALCRL (0.61) | CALCRLRAMP1OPRM1OPRD1 | |
| SCHEMBL31015010 | 0.84 | OPRM1 (0.59) | CALCRLRAMP1OPRM1OPRD1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3952991-A1 | RUSALATIDE ACETATE COMPOSITIONS | Affirmed Pharma, LLC (US) | 2022-02-16 | — | — | EP | claimed |
| WO-2024211447-A1 | TP508 MRNAS | CHRYSALIS BIOTHERAPEUTICS (US) | 2024-10-10 | — | — | WO | disclosed |
| EP-4132948-A1 | TP508 ACUTE THERAPY FOR PATIENTS WITH RESPIRATORY VIRUS INFECTION | Chrysalis Biotherapeutics (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3952991-A1 | RUSALATIDE ACETATE COMPOSITIONS | Affirmed Pharma, LLC (US) | 2022-02-16 | — | — | EP | disclosed |