Anolobine

Anolobine

SCHEMBL29393536

Oc1ccc2c(c1)C[C@H]1NCCc3cc4c(c-2c31)OCO4

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRCAP Q14761 1/20 0.73
BCHE P06276 2/20 0.72
KDM4E B2RXH2 3/20 0.66
POLB P06746 3/20 0.66
ALDH1A1 P00352 2/20 0.66
HPGD P15428 2/20 0.66
KMT2A Q03164 2/20 0.66
LMNA P02545 1/20 0.66
MAPT P10636 1/20 0.66
HTT P42858 1/20 0.66
MCL1 Q07820 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
DYRK1A Q13627 2/20 0.59
HTR2C P28335 4/20 0.48
HTR2A P28223 1/20 0.48
HTR2B P41595 1/20 0.48
DRD2 P14416 4/20 0.47
HSD17B10 Q99714 1/20 0.46
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anolobine SCHEMBL30637512 1.00 PTPRCAP (0.73) PTPRCAPBCHEKDM4EPOLBALDH1A1
SCHEMBL14543629 0.91 PTPRCAP (0.73) PTPRCAPBCHEKDM4EPOLBALDH1A1
SCHEMBL31029804 0.86 PTPRCAP (0.76) PTPRCAPBCHEKDM4EPOLBALDH1A1
Anonaine SCHEMBL15800852 0.85 PTPRCAP (1.00) PTPRCAPBCHEKDM4EPOLBALDH1A1
Anonaine SCHEMBL30049091 0.85 PTPRCAP (1.00) PTPRCAPBCHEKDM4EPOLBALDH1A1
Anonaine SCHEMBL15800856 0.85 PTPRCAP (1.00) PTPRCAPBCHEKDM4EPOLBALDH1A1
Xylopine SCHEMBL6686161 0.84 BCHE (1.00) PTPRCAPBCHEKDM4EPOLBALDH1A1
Xylopine SCHEMBL2595968 0.84 BCHE (1.00) PTPRCAPBCHEKDM4EPOLBALDH1A1
SCHEMBL11891033 0.81 KDM4E (0.71) PTPRCAPBCHEKDM4EPOLBALDH1A1
SCHEMBL30637531 0.81 PTPRCAP (0.72) PTPRCAPBCHEKDM4EPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112289456-B Intramuscular injection complication prevention system and method 无锡市第五人民医院 2022-02-18 CN disclosed