Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRCAP | Q14761 | 2/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 0.69 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anonaine SCHEMBL30049091 | 1.00 | PTPRCAP (1.00) | PTPRCAPBCHEDYRK1APOLBKMT2A | |
| Anonaine SCHEMBL15800856 | 1.00 | PTPRCAP (1.00) | PTPRCAPBCHEDYRK1APOLBKMT2A | |
| SCHEMBL31029804 | 0.86 | PTPRCAP (0.76) | PTPRCAPBCHEDYRK1APOLBKMT2A | |
| Anolobine SCHEMBL29393536 | 0.85 | PTPRCAP (0.73) | PTPRCAPBCHEDYRK1APOLBKMT2A | |
| SCHEMBL14543629 | 0.85 | PTPRCAP (0.73) | PTPRCAPBCHEDYRK1APOLBKMT2A | |
| Anolobine SCHEMBL30637512 | 0.85 | PTPRCAP (0.73) | PTPRCAPBCHEDYRK1APOLBKMT2A | |
| SCHEMBL30637531 | 0.84 | PTPRCAP (0.72) | PTPRCAPBCHEDYRK1APOLBKMT2A | |
| Xylopine SCHEMBL2595968 | 0.82 | BCHE (1.00) | PTPRCAPBCHEDYRK1APOLBKMT2A | |
| Xylopine SCHEMBL6686161 | 0.82 | BCHE (1.00) | PTPRCAPBCHEDYRK1APOLBKMT2A | |
| SCHEMBL30987779 | 0.80 | DYRK1A (0.71) | PTPRCAPBCHEDYRK1APOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194274-A1 | PHENANTHRENE DERIVATIVES FOR USE AS MEDICAMENTS | VALENTIA BIOPHARMA (ES) | 2016-07-07 | — | — | US | disclosed |
| US-20160194274-A1 | PHENANTHRENE DERIVATIVES FOR USE AS MEDICAMENTS | VALENTIA BIOPHARMA (ES) | 2016-07-07 | — | — | US | disclosed |
| WO-2014091020-A1 | PHENANTHRENE DERIVATIVES FOR USE AS MEDICAMENTS | VALENTIA BIOPHARMA (ES) | 2014-06-19 | — | — | WO | disclosed |
| EP-2742974-A1 | Phenanthrene derivatives for use as medicaments | Valentia Biopharma (ES) | 2014-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194274-A1 | PHENANTHRENE DERIVATIVES FOR USE AS MEDICAMENTS | HTT, TARDBP, ATXN2 | PTPRCAP 4766/4885BCHE 1787/4885DYRK1A 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.