Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRCAP | Q14761 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | BCHE | P06276 | 2/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.67 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390321 | 0.87 | KDM4E (0.84) | PTPRCAPPOLBKDM4EKMT2ALMNA | |
| Anonaine SCHEMBL15800852 | 0.86 | PTPRCAP (1.00) | PTPRCAPPOLBKDM4EKMT2ALMNA | |
| Anonaine SCHEMBL30049091 | 0.86 | PTPRCAP (1.00) | PTPRCAPPOLBKDM4EKMT2ALMNA | |
| Anonaine SCHEMBL15800856 | 0.86 | PTPRCAP (1.00) | PTPRCAPPOLBKDM4EKMT2ALMNA | |
| Anolobine SCHEMBL29393536 | 0.86 | PTPRCAP (0.73) | PTPRCAPPOLBKDM4EKMT2ALMNA | |
| Anolobine SCHEMBL30637512 | 0.86 | PTPRCAP (0.73) | PTPRCAPPOLBKDM4EKMT2ALMNA | |
| SCHEMBL14543629 | 0.86 | PTPRCAP (0.73) | PTPRCAPPOLBKDM4EKMT2ALMNA | |
| SCHEMBL11891033 | 0.85 | KDM4E (0.71) | PTPRCAPPOLBKDM4EKMT2ALMNA | |
| SCHEMBL30637531 | 0.84 | PTPRCAP (0.72) | PTPRCAPPOLBKDM4EKMT2ALMNA | |
| Actinodaphnine SCHEMBL674832 | 0.83 | KDM4E (1.00) | PTPRCAPPOLBKDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118703454-A | Cytochrome P450 enzyme from stephania tetrandra and application thereof in biosynthesis of aporphine alkaloid compound | 中国中医科学院中药研究所 | 2024-09-27 | — | — | CN | claimed |
| CN-118547022-A | Preparation method of aporphine alkaloid compound and related catalytic enzyme and application thereof | 中国中医科学院中药研究所 | 2024-08-27 | — | — | CN | claimed |
| CN-118703454-A | Cytochrome P450 enzyme from stephania tetrandra and application thereof in biosynthesis of aporphine alkaloid compound | 中国中医科学院中药研究所 | 2024-09-27 | — | — | CN | disclosed |
| CN-118547022-A | Preparation method of aporphine alkaloid compound and related catalytic enzyme and application thereof | 中国中医科学院中药研究所 | 2024-08-27 | — | — | CN | disclosed |