Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.35 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.35 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.35 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.35 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.35 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.35 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.35 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.35 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746432 | 0.86 | LMNA (0.39) | LMNAPOLBCA1PSMB11PSMD11 | |
| SCHEMBL292669 | 0.86 | LMNA (0.34) | LMNAPOLBPSMB11PSMD11PSMD12 | |
| SCHEMBL292761 | 0.86 | PSMB11 (0.35) | LMNAPOLBCA1PSMB11PSMD11 | |
| SCHEMBL292703 | 0.85 | PLA2G6 (0.35) | LMNACA1PSMB11PSMD11PSMD12 | |
| SCHEMBL292574 | 0.80 | HTT (0.46) | LMNAPOLBCA1PSMB11PSMD11 | |
| SCHEMBL8154874 | 0.80 | HTT (0.46) | LMNAPOLBCA1PSMB11PSMD11 | |
| SCHEMBL3975996 | 0.74 | PSMB11 (0.37) | LMNAPOLBCA1PSMB11PSMD11 | |
| SCHEMBL18186635 | 0.72 | TSHR (0.47) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL6654165 | 0.72 | TSHR (0.47) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL10689073 | 0.72 | TSHR (0.47) | CA1CA2CA7CA9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158790-B2 | Cyclic amine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-04-17 | — | — | US | disclosed |
| EP-2036896-B1 | CYCLIC AMINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2012-03-14 | — | — | EP | disclosed |