SCHEMBL17666809

SCHEMBL17666809

c1ccc2c(-c3cccc4c3oc3ncccc34)nccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.43
MAPT P10636 6/20 0.43
ALDH1A1 P00352 5/20 0.43
HPGD P15428 3/20 0.43
HSD17B10 Q99714 3/20 0.43
GAA P10253 1/20 0.43
NPC1 O15118 5/20 0.43
RAB9A P51151 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
GPR55 Q9Y2T6 1/20 0.43
KMT2A Q03164 2/20 0.42
GLA P06280 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
BCHE P06276 2/20 0.40
HTR1A P08908 1/20 0.39
HTR2A P28223 1/20 0.39
HTR7 P34969 1/20 0.39
HTR6 P50406 1/20 0.39
ACHE P22303 1/20 0.38
TOP2A P11388 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051501 1.00 KDM4E (0.43) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL17215746 0.85 CYP2A6 (0.40) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL25461355 0.85 KDM4E (0.44) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL19094354 0.84 KDM4E (0.48) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22096474 0.84 CYP1A2 (0.44) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL29395390 0.84 KDM4E (0.48) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22170799 0.81 CYP2A6 (0.44) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL23996441 0.79 KDM4E (0.44) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL24796189 0.78 ADORA2A (0.45) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL158912 0.77 BCHE (0.58) KDM4EMAPTALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3968404-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2026-04-01 EP disclosed
EP-3968404-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2022-03-16 EP disclosed
EP-3007244-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-10-27 EP disclosed
US-10998508-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-05-04 US disclosed
US-20170352821-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-12-07 US disclosed
US-9799838-B2 Fluorinated organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-10-24 US disclosed
US-20160285013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-09-29 US disclosed
US-9397302-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-07-19 US disclosed
US-20160104848-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-04-14 US disclosed
EP-3007244-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-04-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10998508-B2 Organic electroluminescent materials and devices ORC3, OCIAD1, ICOSLG KDM4E 3088/4885MAPT 1165/4885ALDH1A1 2142/4885
US-20170352821-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, OCIAD1, ICOSLG KDM4E 3088/4885MAPT 1165/4885ALDH1A1 2142/4885
US-20160104848-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, FARS2, FARSA KDM4E 3162/4885MAPT 1229/4885ALDH1A1 1829/4885
US-20160285013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, FARS2, FARSA KDM4E 3162/4885MAPT 1229/4885ALDH1A1 1829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.