Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366625 | 1.00 | PTPN1 (1.00) | PTPN1PTPN2CES2TOP2ACES1 | |
| SCHEMBL13742655 | 1.00 | PTPN1 (1.00) | PTPN1PTPN2CES2TOP2ACES1 | |
| SCHEMBL28459816 | 0.84 | PTPN1 (0.72) | PTPN1CES2TOP2ACES1PTGES | |
| SCHEMBL29001584 | 0.84 | PTPN1 (0.72) | PTPN1CES2TOP2ACES1PTGES | |
| SCHEMBL1035372 | 0.84 | PTPN1 (0.72) | PTPN1PTPN2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL27753229 | 0.83 | PTPN1 (0.70) | PTPN1PTPN2TOP2AALDH1A1CYP3A4 | |
| SCHEMBL1721809 | 0.81 | PTPN1 (0.67) | PTPN1PTPN2CES2TOP2ACES1 | |
| SCHEMBL28100181 | 0.79 | PTPN1 (0.65) | PTPN1CES2TOP2ACES1PTGES | |
| SCHEMBL14350531 | 0.79 | PTPN1 (0.65) | PTPN1CES2TOP2ACES1RORC | |
| SCHEMBL851609 | 0.79 | PTPN1 (0.65) | PTPN1CES2TOP2ACES1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114099571-A | Composition for treating arthralgia and preparation method thereof | 北京持贞中医技术开发有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-117158438-A | Long-acting quick-killing aerosol formulation containing S-nitenpyram and high-efficiency cyhalothrin | 常州胜杰生命科技股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-114099571-A | Composition for treating arthralgia and preparation method thereof | 北京持贞中医技术开发有限公司 | 2022-03-01 | — | — | CN | disclosed |