Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.67 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721602 | 0.83 | PTPN1 (0.47) | PTPN1CES2CES1PTPN2 | |
| SCHEMBL29397134 | 0.81 | PTPN1 (1.00) | PTPN1PTGESRORCCES2TOP2A | |
| SCHEMBL13742655 | 0.81 | PTPN1 (1.00) | PTPN1PTGESRORCCES2TOP2A | |
| SCHEMBL29366625 | 0.81 | PTPN1 (1.00) | PTPN1PTGESRORCCES2TOP2A | |
| SCHEMBL29001584 | 0.78 | PTPN1 (0.72) | PTPN1PTGESRORCCES2TOP2A | |
| SCHEMBL28459816 | 0.78 | PTPN1 (0.72) | PTPN1PTGESRORCCES2TOP2A | |
| SCHEMBL25329582 | 0.77 | PTPN1 (0.62) | PTPN1PTGESRORCCES2TOP2A | |
| SCHEMBL1721886 | 0.75 | PTPN1 (0.47) | PTPN1CES2CES1PTPN2EGLN2 | |
| SCHEMBL422274 | 0.75 | PTPN1 (0.57) | PTPN1RORCCES2TOP2ACES1 | |
| SCHEMBL422801 | 0.74 | PTPN1 (0.45) | PTPN1RORCCES2TOP2ACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406272-A1 | N-HYDROXY C29-AMIDE DERIVATIVES OF OLEANDRANE | onepharm Research & Development GmbH (AT) | 2012-01-18 | — | — | EP | disclosed |