Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.49 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576935 | 0.90 | TFPI (0.57) | BACE1BACE2CTSD | |
| SCHEMBL31169687 | 0.89 | NPY1R (0.51) | BACE1BACE2KISS1ROPRM1OPRD1 | |
| SCHEMBL29538275 | 0.88 | GNPAT (0.46) | BACE1BACE2CTSD | |
| SCHEMBL31134971 | 0.88 | MME (0.47) | BACE1BACE2OPRM1OPRD1CTSD | |
| SCHEMBL29402983 | 0.87 | BACE1 (0.55) | BACE1BACE2CTSD | |
| SCHEMBL30292594 | 0.87 | CTSB (0.53) | BACE1BACE2CTSD | |
| SCHEMBL29824150 | 0.87 | KISS1R (0.48) | BACE1BACE2KISS1ROPRM1OPRD1 | |
| SCHEMBL30262125 | 0.86 | TFPI (0.57) | BACE1BACE2OPRM1OPRD1OPRK1 | |
| SCHEMBL31516071 | 0.86 | TFPI (0.54) | OPRM1OPRD1OPRK1 | |
| SCHEMBL38659224 | 0.86 | BACE1 (0.60) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196495-A1 | EXENDIN-4 PEPTIDE ANALOGUES | TXP Pharma GmbH (CH) | 2023-06-21 | — | — | EP | disclosed |
| US-11273262-B2 | Medicament delivery device with two drive springs | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2022-03-15 | — | — | US | disclosed |
| WO-2022034062-A1 | EXENDIN-4 PEPTIDE ANALOGUES | TXP PHARMA AG (CH) | 2022-02-17 | — | — | WO | disclosed |